... treatments like minoxidil and finasteride have limitations, highlighting the need for alternative therapies, such as human umbilical cord blood-derived mesenchymal stem cells (HUCB-MSCs). Methods: In this study, forty-eight adult male Wistar albino rats (3 months old) were used. The control group (Group I...

.... Adult male Wistar albino rats ( n = 32, 8 rats in each group) were anesthetized, and their Achilles tendons were prepared for surgical procedures. Group 1 (Cont = control group) was not subjected to any surgery and was used as a control group for baseline values. Group 2 (PR = primary repair group...

... , allogeneic breast cancer cells, and renal tissue that were injected/transplanted into the tail of rats in our pilot studies. In this study, the model of the HLN was established by transferring allogeneic renal tissue in the rat. Intrasinusoidal erythrocytes of the node were the component for producing a red...

...Guus C. Baan; Huub Maas Many questions in human movement sciences are addressed by exploiting the advantages of animal models. However, a 3D graphical model of the musculoskeletal system of the frequently used rat model that includes a sufficient level of detail does not exist. Therefore, the aim...

...) on hypoglycemic testicular injury. We examined 56 testes from 28 animals: 7 rats with insulin-induced hypoglycemia (HG group), 7 hypoglycemic rats which received an intratesticular injection of hUCB-MSCs (HG-MSC group), and 14 untreated control rats. Testosterone level, testicular catalase (CAT) activity...

... whether standardized leaf extracts of ginkgo biloba (EGb761) would improve simvastatin (SIM)-induced muscle changes. Sixty Wistar rats were allotted into six groups: control group, vehicle group receiving 0.5% carboxymethyl cellulose (CMC) for 30 days, SIM group receiving 80 mg/kg/day SIM in 0.5% CMC...

... prenatal brain have not been identified, especially in mid to late stages. In this study, we performed immunohistochemical analyses of NNAT and SOX2 proteins, a nuclear transcription factor and neural stem/progenitor marker, in the rat brain on embryonic days 13.5, E16.5, and E20.5. NNAT signals were...

... throughout the first month after injury. We used 27 male Wistar rats randomly allocated to three groups. In the 9 rats belonging to the first group, the medial collateral ligament was fully transected and left to heal spontaneously without suture. In the 9 rats belonging to the second group, the transected...

... to establishing the possible role of Cdx4 in ARM pathogenesis. Materials and Methods: ARM was induced by ETU on the 10th gestational day (GD10) in rat embryos. Cesarean deliveries were then performed to harvest the embryos. Spatiotemporal expression of Cdx4 was evaluated in normal rat embryos (n = 354) and ARM...

...Jeong-Nam Kim; Ja-Young Yoo; Ju-Young Lee; Ki-Seok Koh; Wu-Chul Song The vibrissal capsular muscle (VCM) of the rat is known to differ from the arrector pili muscle. The purpose of the present study was to characterize the rat VCM morphologically using three-dimensional reconstruction. The rat...

... differentiation, sex determination and genetics. In the present study, we suggest that the rat is also a very important model for the investigation of the mechanisms of germ cell development. To study rat germ cell development and compare it with that of mouse, the germ cell markers germ cell nuclear antigen 1...

.... Bone mesenchymal stem cells Pressure Estrogen receptor F-actin Rat Bone mesenchymal stem cells (BMSCs) are nonhematopoietic stem cells that exist in the bone marrow stroma and have the ability to differentiate into multiple lineages [Pittenger et al., 1999; Meirelles Lda and Nardi...

...Timothy L. Kline; Mair Zamir; Erik L. Ritman Utilizing micro-computed tomography images, the hierarchical structure, interbranch segment lengths and diameters of a hepatic artery, a portal vein, and two biliary trees from intact rat liver lobes were characterized. The data were investigated...

.../infection. In this study, we examined the reestablishment of epithelial and basement membrane barrier structures in a well-established rat model of vocal fold mucosal injury. We observed active cell recruitment culminating in peak hyperplasia at 3 days postinjury, the establishment of robust E-cadherin...

... groups of six 5-week-old male Sprague-Dawley rats underwent fractionated irradiation to the right tibiae over 5 days totaling 17.5 Gy and were then killed at 7, 11, and 16 days following the first radiotherapy fraction. The growth plates were collected from the proximal tibiae bilaterally...

...Mariusz Gajda; Jan A. Litwin; Zbigniew Tabarowski; Olaf Zagólski; Tadeusz Cichocki; Jean-Pierre Timmermans; Dirk Adriaensen Development of autonomic innervation of the tibia was investigated in rat fetuses on gestational days (GD) 17–21 and in juvenile animals on postnatal days (PD) 1–28. Double...

... protein β), protein and metabolic enzymes (albumin, glucose-6-phosphatase, tryptophan 2,3-dioxygenase, arginase 1 and cytochrome P450 7A1) and transporters (organic anion transporting peptide 1, multidrug resistance-associated protein 2 and bile salt export pump), in spheroids derived from rat hepatocytes...

... part of the CSL are immunoreactively positive for androgen receptor. We examined the effects of exposure of the non-steroidal antiandrogen flutamide during the period from gestational day 10 to birth on the development of the CSL and on testis descent. Exposure of male Albino Swiss rats...

...Gisela A. Camihort; Claudia B. Hereñú; Georgina C. Luna; Silvia S. Rodríguez; María I. Bracamonte; Rodolfo G. Goya; Gloria M. Cónsole In previous studies, we assessed the effects of intrapituitary injection of a recombinant adenoviral vector (RAd) harboring the cDNA for rat insulin-like growth...

...-Catenin Glycogen synthase kinase-3β Lithium chloride Preconditioning Skeletal myoblasts Rat Cellular cardiomyoplasty is emerging as a promising therapy for myocardial infarct repair. Skeletal myoblasts (SkMs) appear more attractive compared to other cell types because...