...Nassim Ghaffari-Tabrizi-Wizsy; Silvija Cvitic; Carmen Tam-Amersdorfer; Martin Bilban; Alejandro Majali-Martinez; Karin Schramke; Gernot Desoye; Ursula Hiden Proteases are required for a multitude of cellular processes including homeostatic tissue remodelling, invasion and angiogenesis...

... deepest part just above the dentino-enamel junction (DEJ). The plane of fracture is puzzling because the deepest enamel is deposited earliest and, through the action of the secretory stage enamel protease (Mmp20), is the most mature part of the enamel layer at the time of the onset of Klk4 expression...

... to identify lysosomal proteases that are present in maturation-stage enamel organ. RNA from first molars of 11-day-old mice was collected and expression was initially assessed by RT-PCR and then quantified by qPCR. The pattern of expression of selected proteases was assessed by immunohistochemical staining...