... for chromosomes 12 and 17 (20%) were mixed. The effect of the 3 mentioned anticancer drugs on the chromosomal status was assessed by metaphase spread analysis after selection of the nontoxic conditions. Expression of pluripotency genes was analyzed, and an alkaline phosphatase test was performed to assess...

... is inconsistent and can be confusing, in particular the widely used term pluripotency and its distiction from totipotency. For cells possessing a complete differentiation potential (but lacking an autonomous embryo-structuring capacity) the term omnipotency (or, as recently proposed, plenipotency ) has been...

.... Some of the tubules were branched, which occurs also in vivo, as we show here for the marmoset monkey. Importantly, no teratoma formation by immature pluripotency factor-expressing germ cells was observed. In summary, the reconstituted testicular cords were almost indistinguishable from the cords...

...Sebastian Diecke; Angel Quiroga-Negreira; Torben Redmer; Daniel Besser Human embryonic stem cells (hESCs) can be maintained undifferentiated (pluripotent) or differentiated to basically all functional cell types, depending on the culture conditions used. Culture of hESCs in the presence of medium...

... or in early steps of differentiation. Embryonic stem cells Pluripotency Serial analysis of gene expression Transcriptome analysis Genomatix Framework analysis Mybl2 Maz Stem cells represent basic units of development and regeneration characterized by nearly unlimited self-renewal...

... that maintain and induce pluripotency, as demonstrated by successful reprogramming of somatic cells by fusion with ES cells. Understanding the complex molecular mechanisms underlying ES cell pluripotency should illuminate fundamental properties of stem cells and the process of reprogramming. Proteomics has...