... and plasticity. Hepatocyte growth factor (HGF) has previously been reported to mitigate the complications of various human diseases in animal model studies and in some clinical trials. Besides, human stem cells from the root apical papilla (SCAP) are deemed a better resource of mesenchymal stem cells due...

...Juan Han; Lei Zhang; Xia Li; Ya-ping Chen; Yuan Rong; Bai-gang Yan Loss of Kit protein expression is proven to influence the plasticity of interstitial cells of Cajal (ICCs) and may contribute to gastrointestinal (GI) dysfunctions. The role and fate of Kit negative ICCs are unclear, and cell...

... continues to present significant challenges. Targeting tumour cell plasticity underpinning EMT is an attractive strategy to combat metastasis. Global gene expression profiling and high-content analyses are among the strategies employed to identify novel EMT regulators. In this review, we highlight several...

.... Adipofibroblast Cell division Obesity Plasticity On several occasions, we have described the ability of lipid-containing adipocytes, obtained from the subcutaneous fat depot in beef cattle, to proliferate in vitro [Dodson et al., 2005; Fernyhough et al., 2005a, 2005b, 2005c]. We have termed...

... that somatic stem cells determine the lifespan of an entire tissue, and thus play a key role in the organismal aging process. Recently it has been shown that the developmental potential of somatic stem cells may be far greater than previously anticipated. Although the mechanisms regulating stem cell plasticity...

... potential. The question arises: how plastic are somatic stem cells? To provide a tentative answer, we describe and review here recent investigations into the developmental potentials of two somatic stem cell types, namely hematopoietic and neural stem cells. © 2002 S. Karger AG, Basel 2002 Copyright...

... tissue after injury and a flexibility in the use of these options. Here, we discuss the necessity for amending this definition in the light of recent insight into stem cell biology regarding stem cell heterogeneity, lineage plasticity, clonal fluctuation and cell–environment interactions. We conclude...