...Nazanin Sadat Khademi; Shirin Farivar; Masood Bazrgar; Seyedeh-Nafiseh Hassani; Najmeh Sadat Masoudi; Newsha Haghparast; Mehran Rezaei Larijani Human embryonic stem cells (hESCs) are predisposed to aneuploidy through continual passages. Some reports indicate more sensitivity of aneuploid hESCs...

.... Apoptosis Human embryonic stem cells Nestin Neural differentiation ROCK inhibitor The differentiation of human embryonic stem cells (hESCs) has been extensively studied to generate specific cell types for cell-based therapies and drug screening tests, and to study the early development of human...

... characterized the ability of fetal and adult human dental mesenchyme to promote differentiation of human embryonic stem cell (hESC)-derived ECs (ES-ECs) into ameloblast-lineage cells. ES-ECs were co-cultured either with human fetal dental mesenchymal cells (FDMCs) or with adult dental mesenchymal cells (ADMCs...

... differentiation of human embryonic stem cells (hESCs) is influenced by the size of the differentiating embryoid bodies (EBs). To further understand the dynamics between nutrient mass transfer, EB size, and stem cell differentiation, a transient mass diffusion model of a single hESC EB was constructed. The results...

...Premjit Arpornmaeklong; Michael J. Pressler; Paul H. Krebsbach Purpose: To ensure the efficiency and safety of transplanted human embryonic stem cell (hESC)-derived osteoblast-like cells (hESC-OS) for bone regeneration, this study was designed to determine the effects of continuous cell expansion...

...Shelley E. Brown; Wilbur Tong; Paul H. Krebsbach Human embryonic stem cells (hESCs) hold promise for tissue regeneration therapies by providing a potentially unlimited source of cells capable of undergoing differentiation into specified cell types. Several preclinical studies and a few clinical...

...Sebastian Diecke; Angel Quiroga-Negreira; Torben Redmer; Daniel Besser Human embryonic stem cells (hESCs) can be maintained undifferentiated (pluripotent) or differentiated to basically all functional cell types, depending on the culture conditions used. Culture of hESCs in the presence of medium...

...Søren Holm Among the many ethical issues raised by human embryonic stem cell research (in the following all references to ‘stem cells’ should be read as references to human embryonic stem cells), two have gained specific prominence: (1) whether stem cell research is ethically problematic because...

...Thore C. Brink; Smita Sudheer; Doreen Janke; Justyna Jagodzinska; Marc Jung; James Adjaye Human inner cell mass (ICM) cells isolated from in vitro fertilized blastocysts are the progenitor cells used to establish in vitro stable human embryonic stem cells (hESCs) which are pluripotent and self...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Feeder layer Human embryonic germ cells Human embryonic stem cells...