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Cells Tissues Organs 1–10.
Published Online: 09 October 2023
.... As a biocompatible and conductive scaffold for growth of neural stem cells, three-dimensional graphene foam (3D-GF) supports applications in tissue engineering and regenerative medicine. Although its effects on differentiation have been demonstrated, the effect of 3D-GF scaffold on the generation of BFCNs still...
Cells Tissues Organs 1–10.
Published Online: 03 March 2023
...Guzel Sibgatullina; Rahaf Al Ebrahim; Karina Gilizhdinova; Anna Tokmakova; Artem Malomouzh There are many facts about the possible role of gamma-aminobutyric acid (GABA) in the development and differentiation of cells not only in nervous but also in muscle tissue. In the present study, a primary...
Cells Tissues Organs 1–12.
Published Online: 14 November 2022
... signaling pathways underlying human pancreas development are not yet fully understood, various differentiation protocols are conducted, each considering variable duration, timing, and concentrations of growth factors and small molecules. Therefore, we compared two PP differentiation protocols in static...
Elena Zakirova, Alexander Aimaletdinov, Milana Mansurova, Angelina Titova, Igor Kurilov, Catrin Sian Rutland, Albina Malanyeva, Albert Rizvanov
Cells Tissues Organs 1–16.
Published Online: 01 September 2022
.... The initial stages of extracting MVs from equine MSCs and identifying and characterizing the cultured tendon stem/progenitor cells (TSCs) from rat Achilles tendons were undertaken successfully. The horse MSCs and the rat tendon cells were both capable of differentiating in 3 directions: adipogenic, osteogenic...
Cells Tissues Organs (2020) 208 (1-2): 37–47.
Published Online: 03 April 2020
... differentiation. The first critical step in the study of intestinal cell differentiation is the determination of a suitable in vitro model, which must be as similar as possible to the conditions of a living organism. It is known that HT-29 and Caco2 cell lines derived from human colorectal carcinomas can...
Cells Tissues Organs (2020) 207 (3-4): 127–137.
Published Online: 05 December 2019
..., such as cell differentiation and functional maintenance, during prenatal neurogenesis in the rat brain. Thus, the present observations suggested diverse and active roles of the NNAT protein in neurogenesis. Determining the function of this molecule may assist in the elucidation of the mechanisms involved...
Cells Tissues Organs (2018) 205 (4): 189–196.
Published Online: 27 June 2018
... durations. * p < 0.05 compared to 0 h. Fig. 4. Cell proliferation with different stretching durations. * p < 0.05 compared to 0 h. MyoD is one of the members of MRF (myogenic regulatory factors) that promotes the proliferation and differentiation of myoblasts. MyoD expression, which...
Cells Tissues Organs (2016) 202 (1-2): 85–101.
Published Online: 05 October 2016
... nervous system, a loss of myelin is especially detrimental because of its poor ability to regenerate. Cell therapies such as stem or precursor cell injection have been investigated as stem cells are able to grow and differentiate into the damaged cells; however, stem cell injection alone has been...
Cells Tissues Organs (2016) 201 (6): 412–422.
Published Online: 01 June 2016
... peripheral blood was 15.83 ± 1.61/10 6 , significantly outnumbering that of the nonmobilized group, which was 0.28 ± 0.1/10 6 (p < 0.01). Combining the growth characteristics with the differential capacities of mobilized rPBMSCs towards forming osteocytes, chondrocytes and adipocytes, we further confirmed...
Changming Lu, Samuel Huguley, Chun Cui, Lauren B. Cabaniss, Peter D. Waite, David M. Sarver, Olga A. Mamaeva, Mary MacDougall
Cells Tissues Organs (2016) 201 (1): 26–37.
Published Online: 01 January 2016
... on the regulatory role of Apert FGFR2 signaling in bone formation, whereas its functional role in tooth development is largely unknown. To investigate the role of FGFR signaling in cell proliferation and odontogenic differentiation of human dental cells in vitro, we isolated dental pulp and enamel organ epithelia...
Cells Tissues Organs (2016) 201 (2): 97–108.
Published Online: 05 December 2015
... by functional deletion of the individual E5, E6 or E7, or both E6 and E7 oncogenes in the context of the whole viral genome. These mutants, or the intact wild-type genome, were expressed from the natural viral promoters along with differentiation of epithelial HaCaT cells in three-dimensional collagen raft...
Forum S. Shah, Jie Li, Marilyn Dietrich, Xiying Wu, Mark G. Hausmann, Karl A. LeBlanc, James W. Wade, Jeffrey M. Gimble
Cells Tissues Organs (2015) 200 (3-4): 204–211.
Published Online: 18 June 2015
... compared the differentiation and immunophenotypic features of adipose-derived stromal/stem cells (ASC) isolated from either omental or subcutaneous adipose depots. Human tissue samples were obtained from bariatric and plastic surgical practices at a university-affiliated teaching hospital and a private...
R.J.F.C. do Amaral, P. Benac, L.R. Andrade, M. Farina, C. Bernardazzi, K.D. Arcanjo, A. Palumbo Jr., I.R. Cordeiro, J.M. Brito, M.C. El-Cheikh, F.L. Oliveira
Cells Tissues Organs (2015) 200 (2): 118–131.
Published Online: 09 May 2015
... hematopoiesis, expressing genes involved in myelopoiesis (SCF, G-CSF, GM-CSF, IL-7 and CXCL-12), and differentiated into osteogenic and adipogenic cell lineages. The methodology demonstrated in this work can be considered an excellent experimental model to understand the physiology of the peritoneal wall...
Cells Tissues Organs (2015) 200 (1): 23–30.
Published Online: 21 March 2015
... might exert a positive influence on peripheral nerve regeneration. These include their ability to differentiate into cells resembling Schwann cells and their secretion of a plethora of neurotrophic growth factors. We also review the literature describing the effects of these cells when tested using...
Cells Tissues Organs (2015) 199 (5-6): 393–404.
Published Online: 18 February 2015
... cells were indicative of a state of cell cycle arrest in hypoxia. Furthermore, a decrease in the expression of p21 WAF1/CIP1 and p16 INK4A and fewer β-galactosidase-positive cells suggested a quiescent phenotype rather than a senescent one in hypoxic cells. Compared with normoxic cells, the differential...
Cells Tissues Organs (2015) 199 (5-6): 329–341.
Published Online: 03 December 2014
...Lili Ren; Lijuan Chen; Hui Qi; Furong Li; Feili Gong Human adipose tissue-derived stem cells (hASCs) are considered an ideal tool for the supply of insulin-producing cells to treat diabetes mellitus, with high differentiation efficiency. Islet neogenesis-associated protein (INGAP) is an initiator...
Shaomian Yao, Hongzhi He, Dina L. Gutierrez, Maryam Rezai Rad, Dawen Liu, Chunhong Li, Michael Flanagan, Gary E. Wise
Cells Tissues Organs (2014) 198 (6): 438–447.
Published Online: 08 April 2014
... be restored by addition of hrBMP6. We concluded that DFSCs need to express high levels of BMP6 to maintain their osteogenesis capability. Increased BMP6 expression seen in vivo in the DF may reflect the activation of DFSCs for osteogenic differentiation for bone growth during tooth eruption...
Cells Tissues Organs (2013) 197 (6): 496–504.
Published Online: 14 May 2013
... antibody-conjugated microbeads, and characterized in osteogenic, chondrogenic and adipogenic differentiation. CD271+ cells from umbilical cord blood were slow to proliferate compared with those isolated from bone marrow. While CD271+ cells from bone marrow differentiated into osteogenic, chondrogenic...
Cells Tissues Organs (2013) 197 (5): 399–410.
Published Online: 09 February 2013
...Emma T. Pineda; Robert M. Nerem; Tabassum Ahsan Pluripotent stem cells are attractive candidates as a cell source for regenerative medicine and tissue engineering therapies. Current methods of differentiation result in low yields and impure populations of target phenotypes, with attempts...
Yu Zhou, David L. Mack, J. Koudy Williams, Sayed-Hadi Mirmalek-Sani, Emily Moorefield, So-Young Chun, Jun Wang, Diego Lorenzetti, Mark Furth, Anthony Atala, Shay Soker
Cells Tissues Organs (2013) 197 (4): 269–282.
Published Online: 08 January 2013
..., retinopathy and renal failure. Stem cells, including amniotic fluid-derived stem (AFS) cells - highly expansive, multipotent and nontumorigenic cells - could serve as an appropriate stem cell source for β-cell differentiation. In the current study we tested whether nonhuman primate (nhp)AFS cells ectopically...