...Cecibel M. León-Félix; Andrea Q. Maranhão; Christiani A. Amorim; Carolina M. Lucci Introduction: The decellularized extracellular matrix (dECM) from ovarian tissue could be the best scaffold for the development of a transplantable artificial ovary. Typically, dECM from ovarian tissue has been...

... donation. Decellularized cadaveric nerve tissue alleviates some of these limitations and has demonstrated success clinically. We previously developed an alternative apoptosis-assisted decellularization process for nerve tissue. This new process may result in an ideal scaffold for peripheral nerve...

...Sakthivel Selvaraj; Secunda Rupert; Sangeetha Kadapakkam Nandabalan; Charumathi Anbalagan; Prasanna Srinivasan Rajaram; Jeswanth Satyanesan; Rosy Vennila; Surendran Rajagopal Cell-derived matrices (CDMs) are scaffolds constructed by decellularization of cellular matrices from different tissues...

...Jacquelynn Morrissey; Fernanda C.P. Mesquita; Camila Hochman-Mendez; Doris A. Taylor Bioengineering a solid organ for organ replacement is a growing endeavor in regenerative medicine. Our approach – recellularization of a decellularized cadaveric organ scaffold with human cells – is currently...

...; Regina Coeli dos Santos Goldenberg There are few existing methods for shortening the decellularization period for a human-sized whole-liver scaffold. Here, we describe a protocol that enables effective decellularization of the liver obtained from pigs weigh 120 ± 4.2 kg within 72 h. Porcine livers...

...-free membrane with the mechanical properties required for periodontal treatment is rarely mentioned. Therefore, a procedure for the extraction and modification of BP using sodium dodecyl sulfate (SDS) and glutaraldehyde (GA) was developed. BP was harvested and decellularized using different SDS...

... is increasing with the advancement of technologies and new treatments in human and animal regenerative medicine. Thus, decellularized placental extracellular matrix (ECM) has emerged as a new tool for the production of biological scaffolds for subsequent recellularization and implantation for recovery...

... number of target points, new therapeutic strategies in the field of regenerative medicine are considered. Bioscaffolds along with islet cells would provide bioengineered tissue as a substitute for β-cells. The perfusion-decellularization technique is considered to create such scaffolds since they mimic...

... concern that has led to the pursuit of tissue-engineered liver grafts generated from decellularized liver extracellular matrix and functional cells. Investigative efforts on optimizing both liver decellularization and recellularization protocols have been made in recent decades. In the current review, we...

... concern that has led to the pursuit of tissue-engineered liver grafts generated from decellularized liver extracellular matrix and functional cells. Investigative efforts on optimizing both liver decellularization and recellularization protocols have been made in recent decades. In the current review, we...

... bone marrow-derived mesenchymal stem cell (BM-MSC) behaviors. We generated tissue microenvironments using conditioned medium (CM) and extracellular matrix (ECM) samples obtained from human heart and umbilical cord tissue explant cultures and by tissue decellularization. Mass spectrometry...

...Zhao Huang; Benjamin Kohl; Maria Kokozidou; Stephan Arens; Gundula Schulze-Tanzil Tissue-engineered intervertebral discs (IVDs) utilizing decellularized extracellular matrix (ECM) could be an option for the reconstruction of impaired IVDs due to degeneration or injury. The objective of this study...

...., 2003]. Stem cells Extracellular matrix Decellularization Tissue engineering Placenta Several aspects of placentas are highly variable, including their size and weight (table 1 ). Therefore, they are commonly classified according to their macroscopic appearance, fetal-maternal...

...Alessandro F. Pellegata; Tommaso Dominioni; Filippo Ballo; Silvia Maestroni; M. Adelaide Asnaghi; Gianpaolo Zerbini; Sandro Zonta; Sara Mantero There is still an unmet clinical need for small-caliber artery substitution. Decellularized scaffolds in tissue engineering represent a promising solution...

...Thomas H. Petersen; Elizabeth A. Calle; Maegen B. Colehour; Laura E. Niklason The utility of decellularized native tissues for tissue engineering has been widely demonstrated. Here, we examine the production of decellularized lung scaffolds from native rodent lung using two different techniques...