... with extracellular domains that provide adhesive contacts between neighboring cells. Their intracellular domains bind to the cell cytoskeleton through catenins, including β-catenin. When specific MMPs cleave the cadherin extracellular domain, β-catenin is released and may locate to the cell nucleus...

... demonstrated that a feeder layer of human mesenchymal stromal cells (MSC) could provide a surrogate model as a niche for human HPC. Maintenance of long-term culture-initiating cells was significantly lower on fibroblasts. Methods: Adhesion of HPC to MSC was further analyzed using our recently described...

...-beta: implications for pathological extracellular matrix remodeling in heart valve disease. Circ Res 95: 253–260. In this study, we have provided the first demonstration that interstitial cells isolated from distinct anatomic regions of porcine mitral valves show synthetic, adhesional...

..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Cadherin Adhesion Transcription factor Monoclonal antibody Formalin-fixed...

... for further experiments to explore the influence of surface nanostructures on osteoblast adhesion, differentiation and orientation. By laser-induced oxidation, we produced patterns of parallel Ti oxide lines with different widths (0.2–10 µm) and distances (2–20 and 1,000 µm), but a common height of only 12 nm...

...Egle Avizienyte; Valerie G. Brunton; Valerie J. Fincham; Margaret C. Frame One major function of elevated Src kinase in epithelial cancer cells is to drive adhesion changes that are associated with the mesenchymal transition and metastasis [Jones et al., Br J Cancer 2002;87:1128–1135]. Here we...

...Jun Wang; D. Randall Armant Blastocyst implantation in rodents and primates depends on adhesive interactions between trophoblast cells and the endometrial extracellular matrix. As the blastocyst contacts the uterine basal lamina, cells of the trophectoderm become adhesion-competent and conclude...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Transcription factor Avian retrovirus Podocalyxin CD34 Adhesion...