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Keywords: TP53
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Journal Articles
Subject Area:
Oncology
Case Rep Oncol (2022) 14 (3): 1638–1644.
Published Online: 17 November 2021
... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Germ cell tumour Melanoma Acute megakaryocytic leukaemia TP53 Somatic malignant transformation Extranodal germ cell tumours (GCT) account for 10% of GCTs...
Journal Articles
Subject Area:
Oncology
Case Rep Oncol (2020) 13 (1): 130–138.
Published Online: 13 February 2020
...Beatriz Cirauqui; Teresa Morán; Anna Estival; Vanesa Quiroga; Olatz Etxaniz; Carmen Balana; Matilde Navarro; Salvador Villà; Rosa Ballester; Mireia Margelí Germline mutations in TP53, a tumor suppressor gene, are involved in the development of Li-Fraumeni syndrome, a rare disorder that predisposes...
Journal Articles
Subject Area:
Oncology
Case Rep Oncol (2014) 7 (3): 611–620.
Published Online: 03 September 2014
... pattern in intestinal metaplasia adjacent to the tumor. Furthermore, genetic analysis by direct sequencing revealed a point mutation in the exon 5 of TP53 in the tumor. The mutation presumably harbors a missense mutation from Arg to His at the codon 175 (R175H). R175H has been previously described...