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Keywords: Sirolimus
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Journal Articles
Sirolimus in Infants with Multiple Cardiac Rhabdomyomas Associated with Tuberous Sclerosis Complex
Open AccessSubject Area:
Oncology
Journal:
Case Reports in Oncology
Case Rep Oncol (2018) 11 (2): 425–430.
Published Online: 28 June 2018
...% of patients. Case Report: We treated 3 consecutive infants aged less than 12 months with sirolimus, an oral mTOR inhibitor. All patients achieved significant reductions in cardiac rhabdomyomas. A complete response was documented in 2 patients, while a partial response with tumor debulking greater than 50...