... was receiving palliative chemotherapy. The patient repeatedly developed mild chills, shivering, fever and hypertension during or after infusion of cytotoxic agents such as liposomal irinotecan, gemcitabine, albumin-bound paclitaxel or oxaliplatin. Finally, as the IRR developed immediately after palonosetron, we...

...; they include uncontrolled hypertension, eclampsia, immunosuppressive/chemotherapy medications, anti-angiogenesis inhibitors, sepsis, and autoimmune disorders [ 3 ]. The exact incidence of PRES is not known. The exact pathogenesis is not clear, but the possible mechanisms include breakdown of the cerebral auto...

... discontinued the current treatment with pazopanib. Within 6 days the neurologic symptoms vanished and the patient was discharged. An intermittent hypertension persisted. A follow-up MRI 3 weeks later showed an RPLS-typical cortical infarction in the affected area. RPLS should be considered as the actual reason...