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Case Reports in Oncology 2022, Vol. 15, No. 1
Case Report
Micropapillary Variant of Urothelial Carcinoma in a Hemodialysis Patient
Subject Area:
Oncology
Kyotaro Fukuta; Kiyotaka Iihara; Takahiro Moriyama; Ryoichi Nakanishi; Hirofumi Izaki; Kazuya Kanda; Tohru Inai; Eiji Kudo; Tomoya Fukawa; Kunihisa Yamaguchi; Yasuyo Yamamoto; Masayuki Takahashi; Yasushi Sutou; Hiro-Omi Kanayama
Case Rep Oncol (2022) 15 (1): 462–468.
https://doi.org/10.1159/000524430
Lipomatous (Fat-Forming) Solitary Fibrous Tumor of the Breast: A Case Report of an Uncommon Variant of a Rare Clinical Entity
Subject Area:
Oncology
Case Rep Oncol (2022) 15 (1): 455–461.
https://doi.org/10.1159/000524364
FOLFOXIRI in Pregnant Women with Colorectal Cancer: A Case Report and Review of the Literature
Subject Area:
Oncology
Case Rep Oncol (2022) 15 (1): 447–454.
https://doi.org/10.1159/000524325
Spontaneous Tumor Lysis Syndrome in a Patient with Bulky Chronic Lymphocytic Leukemia Diagnosed after Resolution of Symptoms
Subject Area:
Oncology
Case Rep Oncol (2022) 15 (1): 442–446.
https://doi.org/10.1159/000524198
Bone Marrow Carcinomatosis in a Stage IV Breast Cancer Patient Treated by Letrozole as First-Line Endocrine Therapy
Subject Area:
Oncology
Tsuyoshi Nakagawa; Kumiko Hayashi; Ayumi Ogawa; Goshi Oda; Iichiro Onishi; Masahide Yamamoto; Mio Mori; Tomoyuki Fujioka; Toshiaki Ishikawa; Kentaro Okamoto; Hiroyuki Uetake
Case Rep Oncol (2022) 15 (1): 436–441.
https://doi.org/10.1159/000524152
Unilateral Axillary Lymphadenopathy due to Toxoplasmosis: A Ubiquitous Infectious Disease Important for Differential Diagnosis of Solid Malignancies
Subject Area:
Oncology
Case Rep Oncol (2022) 15 (1): 430–435.
https://doi.org/10.1159/000524177
A Complete Response of Orbital Metastases in Breast Cancer Patient Treated with Oral Chemotherapy: Case Report and Literature Review
Subject Area:
Oncology
Case Rep Oncol (2022) 15 (1): 423–429.
https://doi.org/10.1159/000524276
Human Immature Dental Pulp Stem Cells Did Not Graft into a Preexisting Human Lung Adenocarcinoma
Subject Area:
Oncology
Joyce Macedo da Silva; Rodrigo Pinheiro Araldi; Gabriel Avelar Colozza-Gama; Eduardo Pagani; Ariye Sid; Cristiane Wenceslau Valverde; Irina Kerkis
Case Rep Oncol (2022) 15 (1): 413–422.
https://doi.org/10.1159/000523896
Peripheral Neural Sheath Breast Sarcoma: Case Report and Literature Review
Subject Area:
Oncology
Yency Johana Forero; Martín Ignacio Zapata Laguado; Ximena Briceño; Ricardo Elías Brugés; Fernando Contreras
Case Rep Oncol (2022) 15 (1): 403–412.
https://doi.org/10.1159/000523811
A Case of Hepatopulmonary Syndrome as a Complication of Metastatic Breast Cancer to the Liver
Subject Area:
Oncology
Case Rep Oncol (2022) 15 (1): 399–402.
https://doi.org/10.1159/000524193
Primary Pulmonary Malignant Melanoma Successfully Treated with Immunotherapy in a 90-Year-Old Patient
Subject Area:
Oncology
Case Rep Oncol (2022) 15 (1): 394–398.
https://doi.org/10.1159/000524197
Poorly Differentiated Neuroendocrine Carcinoma of Unknown Primary with Metastasis to the Testis: A Case Report
Subject Area:
Oncology
Case Rep Oncol (2022) 15 (1): 388–393.
https://doi.org/10.1159/000523989
Prolonged Large Seroma Formation after Breast-Conserving Therapy
Subject Area:
Oncology
Case Rep Oncol (2022) 15 (1): 382–387.
https://doi.org/10.1159/000522557
Rare MYH9-ROS1 Fusion Gene-Positive Lung Adenocarcinoma Showing Response to Entrectinib Treatment: A Case Study
Subject Area:
Oncology
Case Rep Oncol (2022) 15 (1): 376–381.
https://doi.org/10.1159/000524071
Poor Outcome due to the Plasmacytoid Variant of Urothelial Carcinoma
Subject Area:
Oncology
Kyotaro Fukuta; Keito Shiozaki; Saki Kobayashi; Ryoichi Nakanishi; Hirofumi Izaki; Kazuya Kanda; Tohru Inai; Eiji Kudo; Tomoya Fukawa; Kunihisa Yamaguchi; Yasuyo Yamamoto; Masayuki Takahashi; Hiro-omi Kanayama
Case Rep Oncol (2022) 15 (1): 369–375.
https://doi.org/10.1159/000524038
Primary Extranodal Marginal Zone Lymphoma of the Renal Pelvis: A Case Report and Review of the Literature
Subject Area:
Oncology
Maria I. Volkova; Yana V. Gridneva; Natalia A. Probatova; Valeria V. Mochalnikova; Kirill A. Turupaev; Vsevolod B. Matveev
Case Rep Oncol (2022) 15 (1): 362–368.
https://doi.org/10.1159/000522555
Acute Exacerbation of Tracheal Obstruction and Severe Respiratory Failure after a Single Dose of 2-Gy Irradiation for Squamous Cell Lung Carcinoma: A Case Report
Subject Area:
Oncology
Keita Kawakado; Takamasa Hotta; Jin Sakamoto; Mika Horie; Misato Kobayashi; Takae Okuno; Yoshihiro Amano; Megumi Hamaguchi; Yukari Tsubata; Noriaki Kurimoto; Takeshi Isobe
Case Rep Oncol (2022) 15 (1): 356–361.
https://doi.org/10.1159/000523941
A Rare Case of Bilateral Pectoralis Major Muscle Defect and Abnormal Muscle
Subject Area:
Oncology
Mayuko Yamamoto; Tomonari Kunihisa; Motoi Baba; Sachiko Mizumoto; Yuji Yamashita; Mayuko Miki; Sachiko Inubushi; Aoi Okamoto; Ryuhei Fujimoto; Hirokazu Tanino
Case Rep Oncol (2022) 15 (1): 351–355.
https://doi.org/10.1159/000523936
Venetoclax: A Novel Therapeutic Agent for CLL with CNS Involvement
Subject Area:
Oncology
Case Rep Oncol (2022) 15 (1): 345–350.
https://doi.org/10.1159/000523858
Multiple Brain Metastases in a Patient with ROS1 Fusion-Positive Lung Adenocarcinoma as a Disease Flare due to Crizotinib Cessation Caused by Disseminated Aseptic Inflammation from Crizotinib-Associated Renal Cysts: A Case Report
Subject Area:
Oncology
Case Rep Oncol (2022) 15 (1): 338–344.
https://doi.org/10.1159/000523737
A Case of Bladder Large Cell Carcinoma with Review of the Literature
Subject Area:
Oncology
Case Rep Oncol (2022) 15 (1): 326–337.
https://doi.org/10.1159/000521607
A Case of Unresectable Combined Hepatocellular-Cholangiocarcinoma Successfully Treated with Lenvatinib
Subject Area:
Oncology
Takahiro Osuga; Koji Miyanishi; Ryo Ito; Shingo Tanaka; Kota Hamaguchi; Hiroyuki Ohnuma; Kazuyuki Murase; Kohichi Takada; Minoru Nagayama; Yasutoshi Kimura; Taro Sugawara; Shintaro Sugita; Ichiro Takemasa; Tadashi Hasegawa; Junji Kato
Case Rep Oncol (2022) 15 (1): 318–325.
https://doi.org/10.1159/000523895
Megestrol Acetate for Heavily Pretreated Metastatic Castration-Resistant Prostate Cancer: An Old Answer for a New Problem
Subject Area:
Oncology
Case Rep Oncol (2022) 15 (1): 312–317.
https://doi.org/10.1159/000522086
Abemaciclib in Patients with End-Stage Renal Disease and Advanced Estrogen Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Breast Cancer: A Report of 2 Cases
Subject Area:
Oncology
Case Rep Oncol (2022) 15 (1): 305–311.
https://doi.org/10.1159/000523856
Unusual Periaortic Mediastinal Recurrence of Pulmonary Adenocarcinoma: When Making Diagnosis Is Really Necessary
Subject Area:
Oncology
Umberto Caterino; Dario Amore; Cristiano Cesaro; Enzo Zamparelli; Flavio Cesaro; Alba Palma; Marcellino Cicalese; Dino Casazza; Raffaella Lucci; Alessandra Cancellieri
Case Rep Oncol (2022) 15 (1): 300–304.
https://doi.org/10.1159/000523736
Retroperitoneal Sentinel Lymph Node Biopsy by Vaginally Assisted Natural Orifices Endoscopic Transluminal Endoscopic Surgery in Early Stage Endometrial Cancer: Description of Technique and Surgeon’s Perspectives after the First Experience
Subject Area:
Oncology
Case Rep Oncol (2022) 15 (1): 291–299.
https://doi.org/10.1159/000523735
Complex Germline K757N Mutation in Non-Small-Cell Lung Cancer: A Case Report
Subject Area:
Oncology
Case Rep Oncol (2022) 15 (1): 285–290.
https://doi.org/10.1159/000523734
Atraumatic Splenic Rupture due to Chronic Myelomonocytic Leukemia Treated with Partial Splenic Artery Embolization
Subject Area:
Oncology
Case Rep Oncol (2022) 15 (1): 277–284.
https://doi.org/10.1159/000522663
Ewing Sarcoma and Primitive Neuroectodermal Tumor of the Thoracic Esophagus: Case Report and Comprehensive Literature Review
Subject Area:
Oncology
Jie Li; Pengfei Sun; Li Ma; Xianhua Min; Binqiang Ye; Yao Zhang; Weiwei Ta; Jiyun Deng; Xiangrong Cao; Chi Dong
Case Rep Oncol (2022) 15 (1): 267–276.
https://doi.org/10.1159/000522152
Hodgkin Lymphoma on Hemodialysis Successfully Treated with Extended Courses of Brentuximab Vedotin
Topic Article Package:
Topic Article Package: ADC (Antibody-Drug Conjugates)
Subject Area:
Oncology
Ayana Uchimura; Hajime Yasuda; Jun Ando; Yasunori Ota; Makoto Sasaki; Tomoiku Takaku; Yutaka Tsukune; Miyuki Tsutsui; Yoko Edahiro; Naoki Watanabe; Tomonori Ochiai; Norio Komatsu; Miki Ando
Case Rep Oncol (2022) 15 (1): 263–266.
https://doi.org/10.1159/000523823
Cervical Edema Extending to the Larynx as Local Cytokine Release Syndrome Following Chimeric Antigen Receptor T-Cell Therapy in a Boy with Refractory Acute Lymphoblastic Leukemia
Subject Area:
Oncology
Haruko Shima; Takumi Kurosawa; Hiroyuki Oikawa; Hisato Kobayashi; Emiri Nishi; Fumito Yamazaki; Kentaro Tomita; Hiroyuki Shimada
Case Rep Oncol (2022) 15 (1): 257–262.
https://doi.org/10.1159/000522669
Diffuse Peritoneal Malignant Mesothelioma Presenting with Abnormal Uterine Bleeding: Case Report
Subject Area:
Oncology
Case Rep Oncol (2022) 15 (1): 251–256.
https://doi.org/10.1159/000522608
BRCA1 Mutation: An Insidious Enemy with Multiple Facets…
Subject Area:
Oncology
Pierrick Godin; Francois P. Duhoux; Filomena Mazzeo; Michel Rojas; Emmanuel Bollue; Aline François; Christine Galant; Julien Coulie; Maude Coyette; Audrey Lentini; Yannick Deswisen; Vasiliki Perlepe; Latifa Fellah; Isabelle Leconte; Martine Berlière
Case Rep Oncol (2022) 15 (1): 238–244.
https://doi.org/10.1159/000521840
Simultaneous Presentation of Glioblastoma Multiforme in Divorced Spouses
Subject Area:
Oncology
Case Rep Oncol (2022) 15 (1): 231–237.
https://doi.org/10.1159/000521201
An Unusual Case of Lorlatinib-Induced Pneumonitis: A Case Report
Subject Area:
Oncology
Case Rep Oncol (2022) 15 (1): 225–230.
https://doi.org/10.1159/000520158
Evading Seizures: Phenobarbital Reintroduced as a Multifunctional Approach to End-of-Life Care
Subject Area:
Oncology
Case Rep Oncol (2022) 15 (1): 218–224.
https://doi.org/10.1159/000522558
Successful Treatment with Radiation Therapy in an Older Patient with Endobronchial Schwannoma
Subject Area:
Oncology
Yoshihiro Nishi; Hiroshi Handa; Hajime Tsuruoka; Takeo Inoue; Saeko Naruki; Tatsuyuki Abe; Masamichi Mineshita
Case Rep Oncol (2022) 15 (1): 212–217.
https://doi.org/10.1159/000522408
Multimodal Imaging in a Case of Presumed Solitary Circumscribed Retinal Astrocytic Proliferation
Subject Area:
Oncology
Case Rep Oncol (2022) 15 (1): 207–211.
https://doi.org/10.1159/000522373
Anaplastic Large Cell Lymphoma Presenting as Ulcerative Facial Mass: A Case Report
Topic Article Package:
Topic Article Package: ADC (Antibody-Drug Conjugates)
Subject Area:
Oncology
Hanna M. Knauss; Logan D. Glosser; Azizullah Beran; Alena N. Sidwell; Waleed Abdulsattar; Roland T. Skeel; Basil E. Akpunonu
Case Rep Oncol (2022) 15 (1): 199–206.
https://doi.org/10.1159/000522267
Metastatic Primary Testicular Neuroendocrine Carcinoma Associated with Somatic Malignant Transformation of Teratoma: A Rare Case Report
Subject Area:
Oncology
Jirapat Wonglhow; Patrapim Sunpaweravong; Chirawadee Sathitruangsak; Kanet Kanjanapradit; Arunee Dechaphunkul
Case Rep Oncol (2022) 15 (1): 191–198.
https://doi.org/10.1159/000521998
Use of Pembrolizumab in End-Stage Renal Disease: A Case Report with Complete Response
Subject Area:
Oncology
Case Rep Oncol (2022) 15 (1): 187–190.
https://doi.org/10.1159/000521979
Management of Esthesioneuroblastoma: A Retrospective Study of 6 Cases and Literature Review
Subject Area:
Oncology
Zenab Alami; Fatima Zahrae Farhane; Amina Bouziane; Samiya Mhirech; Sara Amrani Joutei; Wissal Hassani; Touria Bouhafa
Case Rep Oncol (2022) 15 (1): 176–186.
https://doi.org/10.1159/000521736
Exacerbated Renal and Hematologic Toxicities to Ifosfamide and Doxorubicin-Based Chemotherapy in a Patient with Retroperitoneal Liposarcoma Harboring a Germline Mutation in the WRN Gene
Subject Area:
Oncology
Beatriz Mendes Awni; Carlos Diego Holanda Lopes; Guilherme Harada; Alessandra Corte Real Salgues; Gilmar de Andrade França; Leonardo de Abreu Testagrossa; Marcelo Araujo Queiroz; Adriano Gonçalves e Silva; Fabio de Oliveira Ferreira; Rodrigo Ramella Munhoz
Case Rep Oncol (2022) 15 (1): 170–175.
https://doi.org/10.1159/000521624
SMARCA2/BRM-Deficient Undifferentiated/Rhabdoid Carcinoma of Unknown Primary Site
Subject Area:
Oncology
Yasutaka Tono; Koushi Sukeno; Akira Tsunoda; Kanako Saito; Yoshiki Yamashita; Miki Usui; Katsunori Uchida; Hiroshi Imai; Toshiro Mizuno; Isao Tawara
Case Rep Oncol (2022) 15 (1): 163–169.
https://doi.org/10.1159/000521632
Validity of Weekly Administration of Carboplatin after Carboplatin-Induced SIADH: Two Case Reports and Literature Review
Subject Area:
Oncology
Suguru Fujitsuka; Naoki Horikawa; Teruki Yoshida; Sae Yu; Ryosuke Kuroda; Mitsuru Tsuji; Maki Umemiya; Rei Gou; Yoshihide Inayama; Hirohiko Tani; Kenzo Kosaka
Case Rep Oncol (2022) 15 (1): 156–162.
https://doi.org/10.1159/000522153
Mesothelioma: A Case in a Diagnostic Timeline and the Efficiency of Robot-Assisted Surgery
Subject Area:
Oncology
Paul Zarogoulidis; Kosmas Tsakiridis; Thomas Zarampoukas; Katerina Zarampouka; Dimitris Hatzibougias; Christos Tolis; Stavros Tryfon; Maria Saroglou; Aris Ioannidis; Dimitris Matthaios; Christoforos Kosmidis
Case Rep Oncol (2022) 15 (1): 149–155.
https://doi.org/10.1159/000522114
Nintedanib plus Docetaxel after Immune Checkpoint Inhibitor Failure in Patients with Advanced Non-Small-Cell Lung Cancer: A Case Series
Subject Area:
Oncology
Case Rep Oncol (2022) 15 (1): 138–148.
https://doi.org/10.1159/000520939
Amaurosis Fugax: A Rare Oxaliplatin-Induced Ocular Toxicity – A Report of Three Cases
Subject Area:
Oncology
Case Rep Oncol (2022) 15 (1): 133–137.
https://doi.org/10.1159/000521842
Transfusion Independence Achieved with Combination Fedratinib and Luspatercept in an Elderly Man with Heavily Pretreated Intermediate-2 Risk Primary Myelofibrosis
Subject Area:
Oncology
Case Rep Oncol (2022) 15 (1): 126–132.
https://doi.org/10.1159/000521889
CT and MRI Findings of Inflammatory Myofibroblastic Tumor in the Bladder
Topic Article Package:
Topic Article Package: ADC (Antibody-Drug Conjugates)
Subject Area:
Oncology
Yoshitaka Furukawa; Kazuhiro Kitajima; Hisashi Komoto; Masahiro Zenitani; Takaharu Oue; Hiroyuki Yokoyama; Yoshie Inao; Takashi Yamasaki; Seiichi Hirota; Koichiro Yamakado
Case Rep Oncol (2022) 15 (1): 120–125.
https://doi.org/10.1159/000521921
Gastric Signet-Ring-Cell Adenocarcinoma with Delayed Retroperitoneal Metastasis and Fibrosis
Subject Area:
Oncology
Case Rep Oncol (2022) 15 (1): 114–119.
https://doi.org/10.1159/000521888
Unilateral Ptosis in an Older Adult; a Rare Presentation of Primary Extranodal Hodgkin’s Lymphoma
Subject Area:
Oncology
Case Rep Oncol (2022) 15 (1): 106–113.
https://doi.org/10.1159/000520715
Metastasis of Primary Cutaneous Adenoid Cystic Carcinoma to the Nasal Septum after 17 years: A Case Report
Subject Area:
Oncology
Yohei Takada; Tomoko Takada; Sachie Takayasu; Yuhei Ogino; Yuka Higashiyama; Kenta Fukui; Daiki Sakamoto; Mikiya Asako; Hiroshi Iwai
Case Rep Oncol (2022) 15 (1): 99–105.
https://doi.org/10.1159/000521978
Severe Hyponatremia Masking Central Diabetes Insipidus in a Patient with a Lung Adenocarcinoma
Subject Area:
Oncology
Eduardo Terán Brage; Manuel Heras Benito; Marta Belén Navalón Jiménez; Rosario Vidal Tocino; Edel del Barco Morillo; Emilio Fonseca Sánchez
Case Rep Oncol (2022) 15 (1): 91–98.
https://doi.org/10.1159/000521608
Genetic Analysis of a Family with Multiple Incidences of Prostate Cancer
Subject Area:
Oncology
Case Rep Oncol (2022) 15 (1): 86–90.
https://doi.org/10.1159/000521122
Clinical Utility of Liquid Biopsy to Identify Genomic Heterogeneity and Secondary Cancer Diagnoses: A Case Report
Subject Area:
Oncology
Case Rep Oncol (2022) 15 (1): 78–85.
https://doi.org/10.1159/000521841
Spontaneous Regression of Metachronous Intra-Abdominal Desmoid Tumor in a Patient with Familial Adenomatous Polyposis
Subject Area:
Oncology
Kenji Tsuchihashi; Kyoko Yamaguchi; Ryosuke Taguchi; Kenichi Kohashi; Kayo Ijichi; Yuta Okumura; Michitaka Nakano; Akari Ohno; Tomonobu Hioki; Hozumi Shimokawa; Hiroshi Ariyama; Hitoshi Kusaba; Yoshinao Oda; Koichi Akashi; Eishi Baba
Case Rep Oncol (2022) 15 (1): 71–77.
https://doi.org/10.1159/000521920
A Case Report of Post-Radiotherapy c-MYC-Positive Angiosarcoma of the Breast
Subject Area:
Oncology
Case Rep Oncol (2022) 15 (1): 62–70.
https://doi.org/10.1159/000521069
Post-Immunotherapy Robotic-Assisted Resection for Primary Anorectal Melanoma: A Case Report
Subject Area:
Oncology
Keita Tsutsui; Dai Ogata; Shunsuke Tsukamoto; Konosuke Moritani; Taisuke Mori; Kenjiro Namikawa; Akira Takahashi; Yukihide Kanemitsu; Naoya Yamazaki
Case Rep Oncol (2022) 15 (1): 56–61.
https://doi.org/10.1159/000520858
Comprehensive Genomic Profiling for Therapeutic Decision and Identification of Gene Mutation in Uterine Endometrial Dedifferentiated Carcinoma
Subject Area:
Oncology
Case Rep Oncol (2022) 15 (1): 46–55.
https://doi.org/10.1159/000521897
Quantitative Analysis of Immune-Reactive Cells among Leukocytes Is Useful for the Diagnosis of Drug Eruptions Caused by Bexarotene
Subject Area:
Oncology
Hiromu Chiba; Yumi Kambayashi; Kentaro Ohuchi; Ryo Amagai; Erika Tamabuchi; Akira Hashimoto; Taku Fujimura
Case Rep Oncol (2022) 15 (1): 40–45.
https://doi.org/10.1159/000521843
Photoimmunotherapy for Managing Recurrent Laryngeal Cancer Cervical Lesions: A Case Report
Subject Area:
Oncology
Case Rep Oncol (2022) 15 (1): 34–39.
https://doi.org/10.1159/000521435
A Rare Case of Simultaneous Pheochromocytoma Accompanied with an Ileocecal Neuroendocrine Tumor
Subject Area:
Oncology
Case Rep Oncol (2022) 15 (1): 27–33.
https://doi.org/10.1159/000520384
Two Cases of ALK-Altered Cancers of Unknown Primary Diagnosed by Immunohistochemistry
Subject Area:
Oncology
Yoriko Kato; Kazuhiro Shimazu; Koji Fukuda; Taichi Yoshida; Daiki Taguchi; Hanae Shinozaki; Hiroshi Nanjyo; Hiroyuki Shibata
Case Rep Oncol (2022) 15 (1): 21–26.
https://doi.org/10.1159/000521157
Combination of Reverse Shoulder Prosthesis, Elbow Prosthesis, and Polyetheretherketone: A Modified Total Humeral Replacement for Osteosarcoma Humerus Treatment
Subject Area:
Oncology
Dung Trung Tran; Thanh Duc Tran; Son Ba Nguyen; Sang Quang Tran Nguyen; Quang Minh Dang; Cong Van Tran
Case Rep Oncol (2022) 15 (1): 12–20.
https://doi.org/10.1159/000519599
Abnormal Exacerbation of Moderately Differentiated Gastric Adenocarcinoma in a Patient with TAFRO Syndrome: An Impaired Tumor Immunity?
Subject Area:
Oncology
Tadaaki Inano; Hajime Yasuda; Yutaka Tsukune; Miyuki Tsutsui; Nadila Wali; Harumi Saeki; Kazunori Kajino; Okio Hino; Yasufumi Masaki; Norio Komatsu
Case Rep Oncol (2022) 15 (1): 7–11.
https://doi.org/10.1159/000521463
Sunitinib-Induced Adrenal Crisis in a Patient with Pre-Existing Immunotherapy-Related Hypopituitarism
Subject Area:
Oncology
Case Rep Oncol (2022) 15 (1): 1–6.
https://doi.org/10.1159/000521206
