... filtration rate, the higher the CV risk. Summary: Current data suggest that several uremic toxins lead to vascular inflammation and oxidative stress that, in turn, lead to endothelial dysfunction, changes in smooth muscle cells’ phenotype, and increased degradation of elastin and collagen fibers...

...Gonzalo Ramírez-Guerrero; Claudio Ronco; Thiago Reis Cardiorenal syndrome (CRS) describes the maladaptive relationship between heart and kidney dysfunction, with different pathways perpetuating the pathophysiology. Inflammation is one of these mechanisms. It contributes to the final nonhemodynamic...

... study explores the premise of cfDNA as a marker for apoptosis and inflammation in CRS type 1 patients. cfDNA could potentially serve as an index for noninvasive monitoring of tissue damage and apoptosis in patients with AKI induced by AHF. [email protected] 6 05 2021 17 07...

... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Acute renal failure Cardiac surgery Inflammation Biomarkers Nutrition Cardiac...

... than controls. Such findings support that cystogenesis and inflammation are associated with endothelial dysfunction, even in the early stages of ADKPD. [email protected] 13 05 2020 7 08 2020 17 11 2020 © 2020 S. Karger AG, Basel 2020 Copyright / Drug Dosage...

..., small noncoding RNAs, and epigenetics play pivotal roles in the development of CRS. In this review, we will focus on neurohormonal, endocrine, and immune dysregulation and inflammation as mechanisms involved in the pathogenesis of CRS. [email protected] 12 04 2019 30 04 2019...

... ventricular assist device Biomarkers of fibrosis Biomarkers of kidney injury Inflammation In heart failure patients, left ventricular assist device (LVAD) therapy improves cardiac output and organ perfusion [ 1 ]. In most patients with end-stage heart failure, renal function, assessed as glomerular...

...Grazia Maria Virzì; Andrea Breglia; Alessandra Brocca; Massimo de Cal; Chiara Bolin; Giorgio Vescovo; Claudio Ronco Background: Cardiorenal syndrome type 1 (CRS type 1) is characterized by a rapid worsening of cardiac function leading to acute kidney injury (AKI). Inflammation and oxidative stress...

... that, according to standard clinical guidelines, reduce CV risk such as antihypertensive therapy, diet, exercise, and statins are not similarly effective in the hemodialysis population. This raises the question of whether additional risk factors, such as enhanced inflammation and oxidative stress, may drive...

... Inflammation Atherosclerosis Cardiac surgery Acute kidney injury (AKI) is considered an independent risk factor for morbidity and mortality in hospitalised patients, especially in those who have undergone major surgery [ 1,2 ]. The severity and progression of AKI have significant deleterious effects...

... and cardiovascular outcome. However, the relative importance of inflammation versus kidney function on plasma NGAL levels is uncertain, making the interpretation of plasma NGAL unclear. Accordingly, we investigated the relationship between plasma NGAL, inflammation and kidney function in patients with myocardial...

...-known kidney damage risk factors as well. - Model D: all variables in models A-C combined. Community TNF-α Glomerular filtration Albumin/creatinine ratio Chronic kidney disease Inflammation Soluble receptors for tumor necrosis factor (TNF)-α (sTNFRs) in plasma have been shown...

.... Cardiorenal syndrome Acute heart failure Apoptosis Immune-mediated mechanism Monocytes Inflammation ‘Organ crosstalk' is fundamental for the homeostasis and optimal function of all systems. However, in a disease condition, there is a dysregulation of this system, and the diseased organ influences...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Tumor necrosis factor Laplace regression Mortality Inflammation Based on the associations between sTNFRs, mortality and deterioration of kidney function [ 5,7,11 ], we...

..., arterial stiffness and inflammation. The aim of this study was to compare blood pressure (BP) and metabolic parameters with cardiovascular changes [cardiothoracic ratio (CTR), aortic arch calcification (AAC) and LV mass index (LVMI)] between PD and HD patients. Materials and Methods: 45 patients (23 HD...

...), whereas L/H treatment had no significant effect. Our findings suggest that, in addition to effective BP reduction, A/O differentially regulates markers of inflammation and obesity, thereby potentially providing greater vascular protection. 19 05 2013 14 08 2013 2 10 2013 © 2013 S...

... pathogenesis, include the attending roles of inflammation and oxidative stress. Emphasis has been placed on obesity as a modifiable risk factor which, when addressed, provides a reduction in the rate of cancer deaths. In a second part to be published in the next issue of this journal, the relationship between...

...Diptesh Gupta; Michael Gardner; Adam Whaley-Connell Malnutrition and inflammation are strong predictors of mortality in advanced kidney disease, especially in patients on renal replacement therapy. The complex relationship between kidney disease, uremia, and malnutrition significantly contributes...