...Ken Mizokami; Akiko Watanabe; Eriko Yamaguchi; Akira Saito We present a case of severe bowel perforation during lenvatinib treatment for advanced hepatocellular carcinoma. Although the Hartmann’s procedure was performed, the patient died 48 h after the operation. The histopathological findings...

...Yuji Inada; Seiji Hattori; Yasuhiko Fujita; Teruyoshi Amagai The hepatocellular carcinoma (HCC) with intrahepatic and bone metastasis shows poor survival of averagely 3 months. The bone metastasis and HCC itself might cause cancer-associated pain. An intrathecal (IT) analgesia might contribute...

...Seok Bae Kim There are only 13 cases of complete remission after sorafenib use in advanced hepatocellular carcinoma (HCC) worldwide. We herein report a rarer case in which the patient was cured after only 20 days of sorafenib use. A 61-year-old male patient was diagnosed with a huge HCC. The mass...

.... Herein, we report a case of a hepatic EHE presenting synchronously with a hepatocellular carcinoma (HCC). To the best of our knowledge, this is the second case report of synchronous hepatic EHE and HCC. An 84-year-old man presented with back pain. During examination, a tumor in liver segment 3...

.... Histopathological examination showed a hepatocellular carcinoma with areas of HNF1a-HCA (H-HCA). This case shows that malignant transformation is possible in H-HCA. We present our preoperative decision-making process, as well as the role of imaging techniques in this rare case. A 66-year-old woman was referred...

...Aya Hammami; Nour Elleuch; Hanen Jaziri; Yasser Ben Cheikh; Ahlem Braham; Salem Ajmi; Aida Ben Slama; Mehdi Ksiaa; Ali Jmaa Hepatocellular carcinoma (HCC) is the most frequent type of liver cancer. Liver cirrhosis of any etiology is considered the main risk factor for the development of HCC...

...Zhe Yang; Bulat Abdrakhimov; Shuo Wang; Qin-Fen Xie; Shu-Sen Zheng Current strategy for treatment of hepatocellular carcinoma (HCC) based on Barcelona-Clinic Liver Cancer (BCLC) criteria dictates that patients with advanced-stage HCC are to only receive treatment with tyrosine kinase inhibitors...

... challenge for the surgeon. In the present study, right hemihepatectomy via the anterior approach was performed for a 68-year-old hepatocellular carcinoma (HCC) patient with SIT. SIT was diagnosed by chest X-ray and computed tomography. The tumors were located in segments VIII and VI of the liver...

... are surviving into adulthood and are at risk of hepatic sequalae. The ideal timeline and method of hepatic surveillance in the Fontan population remains to be defined. In this case, the patient was diagnosed with hepatocellular carcinoma more than 20 years after undergoing the Fontan procedure...

...Atsunori Tsuchiya; Takeshi Suda; Chiyumi Oda; Atsushi Kimura; Kazunori Hosaka; Naruhiro Kimura; Kentaro Tominaga; Kazunao Hayashi; Masaaki Takamura; Shuji Terai Hepatic progenitor cell (HPC) marker-positive hepatocellular carcinomas (HCCs) have recently been extensively analyzed...

... with moderately severe ZSD (formerly known as neonatal adrenoleukodystrophy), with development of hepatocellular carcinoma (HCC) at age 19 years. Our patient was initially treated with CA within an investigator-initiated compassionate use program (NCT00007020) that was followed by an open-label, nonrandomized...

...Tomohiko Taniai; Yoshihiro Shirai; Hiroaki Shiba; Taro Sakamoto; Kenei Furukawa; Katsuhiko Yanaga Several possible mechanisms for spontaneous regression of hepatocellular carcinoma (HCC) have been reported. Spontaneous complete regression of HCC is extremely rare. We herein report a case...

...Tomohiko Taniai; Koichiro Haruki; Hiroaki Shiba; Shinji Onda; Taro Sakamoto; Katsuhiko Yanaga Simultaneous resection of synchronous hepatocellular carcinoma (HCC) and pancreatic ductal adenocarcinoma (PDAC) is extremely rare. Case 1 is a 64-year-old woman, who had undergone anterior resection...

...Yudai Koya; Tomohiro Suzuki; Mayumi Tai; Osamu Ichii; Nobuo Matsuhashi; Yutaka Ejiri; Michihiko Shibata; Masaru Harada An 83-year-old man underwent transcatheter arterial chemoembolization (TACE) for a 20-mm hepatocellular carcinoma (HCC) in Couinaud’s segment 4. Computed tomography (CT) 4 months...

...Natascha Roehlen; Richard F. Knoop; Katharina Laubner; Jochen Seufert; Henning Schwacha; Robert Thimme; Andreas Fischer Drug-eluting bead transarterial chemoembolization (DEB-TACE) is a well-established, minimally invasive interventional treatment for nonresectable hepatocellular carcinoma (HCC...

...Sara Naimimohasses; Omar El Sherif; Mohammad Ashfaq; Niamh Nolan; Masood Iqbal; Susan McKiernan; Suzanne Norris The spontaneous seroclearance of hepatitis B upon development of a hepatocellular carcinoma (HCC) is extremely rare. To date, there has been one published case series reporting hepatitis...

...Rafael Sartori Balbinot; Ana Laura Facco Muscope; Mateus Dal Castel; Silvana Sartori Balbinot; Raul Angelo Balbinot; Jonathan Soldera Although extrahepatic metastases from hepatocellular carcinoma (HCC) are present in only 5–15% of cases, they are certainly factors associated with poor prognosis...

...Mashal Salehi; The Yee; Eric Alatevi; Yamin Thein Intracavitary cardiac extension remains an unusual site of extrahepatic metastasis in patients with hepatocellular carcinoma. While patients can present with signs and symptoms suggestive of right-sided heart failure, it may be totally asymptomatic...

...Toru Setsu; Atsunori Tsuchiya; Takayuki Watanabe; Takuro Nagoya; Satoshi Ikarashi; Kazunao Hayashi; Junji Yokoyama; Satoshi Yamagiwa; Shuji Terai Alpha-fetoprotein (AFP)-L3 was originally reported as a hepatocellular carcinoma (HCC)-specific tumor marker, and recent accumulation of evidence has...

...Severin Gloor; Kai Oliver Jensen; Stefan Breitenstein; Christoph A. Binkert; Eliane Angst; Franc Heinrich Hetzer Spontaneous ruptures of hepatocellular carcinoma (HCC) are rare. Nevertheless they may lead to difficult decisions in the emergency situation. The acute therapies include conservative...