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Keywords: Direct-acting antivirals
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Journal Articles

Portal Vein Aneurysm in a Patient with Cirrhosis Type C Controlled by Direct-Acting Antiviral Treatment

Subject Area:
Gastroenterology
Sena Higashi, Tasuku Nakabori, Kaori Mukai, Yusuke Seiki, Ko Watsuji, Takeru Hirao, Yasuharu Kawamoto, Makiko Urabe, Yugo Kai, Ryoji Takada, Takuo Yamai, Kenji Ikezawa, Hiroyuki Uehara, Kazuyoshi Ohkawa
Journal: Case Reports in Gastroenterology
Case Rep Gastroenterol (2024) 18 (1): 74–80.
https://doi.org/10.1159/000535957
Published Online: 16 February 2024
... with elbasvir-grazoprevir for 12 weeks, and HCV disappeared. After achieving sustained virological response, liver fibrosis improved and the PVA progression ceased. Conclusion: HCV clearance by direct-acting antiviral treatment not only regressed liver fibrosis but may have also restrained the progression...
View article titled, Portal Vein Aneurysm in a Patient with Cirrhosis Type C Controlled by <span class="search-highlight">Direct</span>-<span class="search-highlight">Acting</span> <span class="search-highlight">Antiviral</span> Treatment
Open the PDF for Portal Vein Aneurysm in a Patient with Cirrhosis Type C Controlled by <span class="search-highlight">Direct</span>-<span class="search-highlight">Acting</span> <span class="search-highlight">Antiviral</span> Treatment in another window
Journal Articles

Onset of Oral Lichen Planus Led to Direct-Acting Antiviral Therapy in a Patient with Long-Term Hepatitis C: The Role of a Dentist as Gatekeeper

Subject Area:
Topic Article Package: ADC (Antibody-Drug Conjugates) , Gastroenterology
Yumiko Nagao, Masahide Tsuji
Journal: Case Reports in Gastroenterology
Case Rep Gastroenterol (2023) 17 (1): 26–33.
https://doi.org/10.1159/000528681
Published Online: 09 January 2023
...Yumiko Nagao; Masahide Tsuji Oral lichen planus (OLP), a chronic inflammatory mucocutaneous disease, is an extrahepatic manifestation of a hepatitis C virus infection. In recent years, direct-acting antivirals (DAAs) have made great strides in the treatment of hepatitis C. However, there might...
View article titled, Onset of Oral Lichen Planus Led to <span class="search-highlight">Direct</span>-<span class="search-highlight">Acting</span> <span class="search-highlight">Antiviral</span> Therapy in a Patient with Long-Term Hepatitis C: The Role of a Dentist as Gatekeeper
Open the PDF for Onset of Oral Lichen Planus Led to <span class="search-highlight">Direct</span>-<span class="search-highlight">Acting</span> <span class="search-highlight">Antiviral</span> Therapy in a Patient with Long-Term Hepatitis C: The Role of a Dentist as Gatekeeper in another window
Journal Articles

A Hepatitis C Virus-Associated Decompensated Cirrhotic Patient Who Showed the Disappearance of Hepatic Encephalopathy, Ascites, and Pleural Effusion by Antiviral Therapy with Sofosbuvir/Velpatasvir

Subject Area:
Gastroenterology
Kazuo Tarao, Akito Nozaki, Hirokazu Komatsu
Journal: Case Reports in Gastroenterology
Case Rep Gastroenterol (2021) 15 (1): 436–442.
https://doi.org/10.1159/000511749
Published Online: 27 April 2021
...Kazuo Tarao; Akito Nozaki; Hirokazu Komatsu Oral direct-acting antivirals (DAAs) are the main therapy for hepatitis C virus (HCV)-associated liver disease in Japan. Moreover, many DAAs include an indication for compensated liver cirrhosis. However, patients with decompensated HCV-associated...
View article titled, A Hepatitis C Virus-Associated Decompensated Cirrhotic Patient Who Showed the Disappearance of Hepatic Encephalopathy, Ascites, and Pleural Effusion by Antiviral Therapy with Sofosbuvir/Velpatasvir
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Journal Articles

Rapid Regression of B-Cell Non-Hodgkin’s Lymphoma after Eradication of Hepatitis C Virus by Direct Antiviral Agents

Subject Area:
Topic Article Package: Moksha , Gastroenterology
Shunji Hirose, Yoko Yamaji, Kota Tsuruya, Yoshiaki Ogawa, Masashi Miyaoka, Tatehiro Kagawa
Journal: Case Reports in Gastroenterology
Case Rep Gastroenterol (2019) 13 (2): 336–341.
https://doi.org/10.1159/000501546
Published Online: 26 July 2019
... to Direct-Acting Antiviral Therapy for Hepatitis C Virus Infection?   Gastroenterology . 2019   Jan ; 156 ( 2 ): 446 – 460.e2 . 10.1053/j.gastro.2018.10.033 30367836 0016-5085 4. Morgan   RL , Baack   B , Smith   BD , Yartel   A , Pitasi   M , Falck-Ytter   Y . Eradication...
View article titled, Rapid Regression of B-Cell Non-Hodgkin’s Lymphoma after Eradication of Hepatitis C Virus by Direct Antiviral Agents
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Journal Articles

Successful Treatment of Oral Lichen Planus with Direct-Acting Antiviral Agents after Liver Transplantation for Hepatitis C Virus-Associated Hepatocellular Carcinoma

Subject Area:
Gastroenterology
Yumiko Nagao, Kazunori Nakasone, Tatsuji Maeshiro, Nao Nishida, Kanae Kimura, Yuji Kawahigashi, Yasuhito Tanaka, Michio Sata
Journal: Case Reports in Gastroenterology
Case Rep Gastroenterol (2018) 11 (3): 701–710.
https://doi.org/10.1159/000484132
Published Online: 29 November 2017
... lichen planus (OLP) is one such extrahepatic manifestation of HCV infection. Recently, direct-acting antivirals (DAA) have proved to be highly effective and safe for the eradication of HCV. Herein, we report a case of OLP accompanied by HCV-related hepatocellular carcinoma (HCC) that disappeared after...
View article titled, Successful Treatment of Oral Lichen Planus with <span class="search-highlight">Direct</span>-<span class="search-highlight">Acting</span> <span class="search-highlight">Antiviral</span> Agents after Liver Transplantation for Hepatitis C Virus-Associated Hepatocellular Carcinoma
Open the PDF for Successful Treatment of Oral Lichen Planus with <span class="search-highlight">Direct</span>-<span class="search-highlight">Acting</span> <span class="search-highlight">Antiviral</span> Agents after Liver Transplantation for Hepatitis C Virus-Associated Hepatocellular Carcinoma in another window
Journal Articles

A Hepatitis C Virus-Associated Chronic Hepatitis Patient Developing Various Adverse Events Including Severe Gingivitis, Gingival Bleeding, and Inflammation of Genital Vulva during the Course of Antiviral Therapy with Elbasvir/Grazoprevir

Subject Area:
Gastroenterology
Kazuo Tarao, Akira Sato
Journal: Case Reports in Gastroenterology
Case Rep Gastroenterol (2018) 11 (3): 736–741.
https://doi.org/10.1159/000484135
Published Online: 29 November 2017
...Kazuo Tarao; Akira Sato Oral direct-acting antivirals comprise the main therapy for hepatitis C virus (HCV)-associated liver disease in Japan. Daclatasvir/asunaprevir is the primary agent and sofosbuvir/ledipasvir is the secondary agent for HCV genotype 1b. Ombitasvir/paritaprevir/ritonavir...
View article titled, A Hepatitis C Virus-Associated Chronic Hepatitis Patient Developing Various Adverse Events Including Severe Gingivitis, Gingival Bleeding, and Inflammation of Genital Vulva during the Course of Antiviral Therapy with Elbasvir/Grazoprevir
Open the PDF for A Hepatitis C Virus-Associated Chronic Hepatitis Patient Developing Various Adverse Events Including Severe Gingivitis, Gingival Bleeding, and Inflammation of Genital Vulva during the Course of Antiviral Therapy with Elbasvir/Grazoprevir in another window
Journal Articles

A Hepatitis C Virus-Associated Cirrhotic Patient Developing Interstitial Pneumonia during the Course of Antiviral Therapy with Ombitasvir/Paritaprevir/Ritonavir

Subject Area:
Gastroenterology
Kazuo Tarao, Kouzo Yamada
Journal: Case Reports in Gastroenterology
Case Rep Gastroenterol (2017) 11 (2): 369–376.
https://doi.org/10.1159/000462965
Published Online: 09 June 2017
...Kazuo Tarao; Kouzo Yamada Oral direct-acting antivirals (DAAs) are the main therapy for hepatitis C virus (HCV)-associated liver disease in Japan. Daclatasvir/asunaprevir is the first agent and sofosbuvir/ledipasvir is the secondary agent for HCV genotype 1b. More recently, ombitasvir/paritaprevir...
View article titled, A Hepatitis C Virus-Associated Cirrhotic Patient Developing Interstitial Pneumonia during the Course of Antiviral Therapy with Ombitasvir/Paritaprevir/Ritonavir
Open the PDF for A Hepatitis C Virus-Associated Cirrhotic Patient Developing Interstitial Pneumonia during the Course of Antiviral Therapy with Ombitasvir/Paritaprevir/Ritonavir in another window
Journal Articles

Successful Treatment for Chronic Hepatitis C-Autoimmune Hepatitis Overlap Syndrome due to Daclatasvir and Asunaprevir

Subject Area:
Gastroenterology
Ayumi Sugiura, Shuichi Wada, Hiromitsu Mori, Takefumi Kimura, Yoshiaki Matsuda, Naoki Tanaka, Eiji Tanaka, Kendo Kiyosawa
Journal: Case Reports in Gastroenterology
Case Rep Gastroenterol (2017) 11 (2): 305–311.
https://doi.org/10.1159/000475752
Published Online: 17 May 2017
... treated with the direct-acting antivirals (DAA), daclatasvir and asunaprevir. A 50-year-old man was referred to our hospital because of positive anti-HCV antibody and liver dysfunction at a health checkup. Blood tests showed increased immunoglobulin G (IgG) and a high titer of antinuclear antibody (ANA...
View article titled, Successful Treatment for Chronic Hepatitis C-Autoimmune Hepatitis Overlap Syndrome due to Daclatasvir and Asunaprevir
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Journal Articles

Use of Direct-Acting Antivirals for the Treatment of Hepatitis C Virus-Associated Oral Lichen Planus: A Case Report

Subject Area:
Gastroenterology
Kenji Misaka, Takashi Kishimoto, Yuji Kawahigashi, Michio Sata, Yumiko Nagao
Journal: Case Reports in Gastroenterology
Case Rep Gastroenterol (2017) 10 (3): 617–622.
https://doi.org/10.1159/000450679
Published Online: 28 October 2016
... manifestations of HCV infection. Direct-acting antivirals (DAA) are highly effective and safe for the eradication of HCV. However, there is a lack of information regarding the association between HCV-associated OLP and interferon (IFN)-free DAA therapy. Herein, we present the case of a 60-year-old female who...
View article titled, Use of <span class="search-highlight">Direct</span>-<span class="search-highlight">Acting</span> <span class="search-highlight">Antivirals</span> for the Treatment of Hepatitis C Virus-Associated Oral Lichen Planus: A Case Report
Open the PDF for Use of <span class="search-highlight">Direct</span>-<span class="search-highlight">Acting</span> <span class="search-highlight">Antivirals</span> for the Treatment of Hepatitis C Virus-Associated Oral Lichen Planus: A Case Report in another window
Journal Articles

Successful Management of Graft Reinfection of HCV Genotype 2 in Living Donor Liver Transplantation from a Hepatitis B Core Antibody-Positive Donor with Sofosbuvir and Ribavirin

Subject Area:
Gastroenterology
Reina Sasaki, Tatsuo Kanda, Masayuki Ohtsuka, Shin Yasui, Yuki Haga, Masato Nakamura, Masayuki Yokoyama, Shuang Wu, Shingo Nakamoto, Makoto Arai, Hitoshi Maruyama, Masaru Miyazaki, Osamu Yokosuka
Journal: Case Reports in Gastroenterology
Case Rep Gastroenterol (2016) 10 (2): 366–372.
https://doi.org/10.1159/000447423
Published Online: 20 July 2016
...Reina Sasaki; Tatsuo Kanda; Masayuki Ohtsuka; Shin Yasui; Yuki Haga; Masato Nakamura; Masayuki Yokoyama; Shuang Wu; Shingo Nakamoto; Makoto Arai; Hitoshi Maruyama; Masaru Miyazaki; Osamu Yokosuka Direct-acting antivirals (DAAs) are relatively safe and highly effective for the eradication...
View article titled, Successful Management of Graft Reinfection of HCV Genotype 2 in Living Donor Liver Transplantation from a Hepatitis B Core Antibody-Positive Donor with Sofosbuvir and Ribavirin
Open the PDF for Successful Management of Graft Reinfection of HCV Genotype 2 in Living Donor Liver Transplantation from a Hepatitis B Core Antibody-Positive Donor with Sofosbuvir and Ribavirin in another window
Journal Articles

Successful Eradication of Hepatitis C Virus by Interferon-Free Regimens in Two Patients with Advanced Liver Fibrosis following Kidney Transplantation

Subject Area:
Gastroenterology
Reina Sasaki, Tatsuo Kanda, Shin Yasui, Yuki Haga, Masato Nakamura, Mutsumi Yamato, Shuang Wu, Shingo Nakamoto, Makoto Arai, Shigeru Mikami, Hideaki Miyauchi, Hisahiro Matsubara, Osamu Yokosuka
Journal: Case Reports in Gastroenterology
Case Rep Gastroenterol (2016) 10 (2): 248–256.
https://doi.org/10.1159/000445374
Published Online: 27 May 2016
... a kidney transplant. It has been reported that direct-acting antivirals (DAAs) are relatively safe and highly effective for the eradication of HCV in patients who are liver transplant recipients. In the present study, we investigated HCV eradication via interferon-free therapies with DAAs in two HCV...
View article titled, Successful Eradication of Hepatitis C Virus by Interferon-Free Regimens in Two Patients with Advanced Liver Fibrosis following Kidney Transplantation
Open the PDF for Successful Eradication of Hepatitis C Virus by Interferon-Free Regimens in Two Patients with Advanced Liver Fibrosis following Kidney Transplantation in another window