...Netanel Krugliak; Mark S. Silverberg Introduction: Curcumin and QingDai (QD, indigo) are two herbal extracts used in traditional medicine. A combination of curcumin with QD (CurQD) was reported to be effective in ulcerative colitis, but its effectiveness in Crohn’s disease (CD) is unknown. We...

...Naveena Luke; Tianyu She; Divya Roy; Toyooki Sonoda; Seymour Katz Introduction: Chronic gastrointestinal bleeding in patients with Crohn’s disease presents diagnostic challenges. Adult intussusception is rare and typically caused by a pathological lead point, such as a tumor or inflammatory lesion...

...Naveena Luke; Inna Carmela De Leon; Shayan Azizi; Seymour Katz Introduction: Cryptogenic multifocal ulcerative stenosing enteritis (CMUSE) is a rare and underrecognized small bowel disorder that often mimics Crohn’s disease, leading to delays in diagnosis and misdirected treatment. Given its...

... Crohn’s disease Hepatic abscess Aseptic hepatic abscess Inflammatory bowel disease (IBD) results from a proinflammatory cascade in genetically susceptible individuals as a response to certain environmental antigens [ 1 ]. IBD is typically a relapsing-remitting disease and can have...

... the use of a glucagon-like peptide-2 (GLP-2) analog in the nutritional management of an SBS patient dependent on total parenteral nutrition (TPN). Case Presentation: A 29-year-old woman with a significant medical history of Crohn’s disease leading to SBS was traditionally dependent on TPN for sustenance...

...Anouk Lehmann; Juerg Vosbeck; Diego Kyburz; Petr Hruz; Jan Hendrik Niess Introduction: Treatment of Crohn’s disease (CD) and axial spondyloarthritis (axSpA) is challenging, with CD refractory to anti-TNF antibodies. Here, we present for the first time a case treated with dual-targeted therapy (DTT...

... disease Gastrointestinal bleed Inflammatory bowel disease (IBD) is a chronic gastrointestinal inflammatory condition, composed of Crohn’s disease and ulcerative colitis. IBD predisposes to increased risk of developing venous thromboembolism (VTE), encompassing deep vein thrombosis (DVT...

...Takaomi Seki; Katsuya Osone; Hiroomi Ogawa; Takuhisa Okada; Takuya Shiraishi; Makoto Sohda; Ken Shirabe; Hiroshi Saeki Introduction: Crohn’s disease (CD) is complicated by intestinal strictures and fistula formation; however, intestinal perforation is relatively rare. Case Presentation: Following...

... iron infusions. Case Presentation: We present the case of a 37-year-old man with active Crohn’s disease, presenting with difficulty walking and fractures of the vertebrae and calcaneus. He had long-standing hypophosphatemia. Nutritional causes for hypophosphatemia were considered in the first instance...

... for Crohn’s disease. Skin biopsy of the affected area showed perivascular extravasation of erythrocytes, neutrophils, eosinophils and vascular damage surrounding blood vessels associated with fibrin, consistent with LCV. Patient was treated with topical steroids and subsequently transitioned to ustekinumab...

... further evaluation, imaging showed obstruction at the terminal ileum. Based on the holistic clinical presentation, we initially thought that this patient was experiencing symptoms of early onset Crohn’s disease. Gastroenterology evaluated the patient and was uncertain of the formal diagnosis. Colonoscopy...

..., however, Crohn’s disease was diagnosed in 2016. The patient began therapy with azathioprine and prednisolone, and later developed hormone dependence and osteoporosis. In 2020, against the background of immunosuppressive therapy, the patient has an exacerbation, especially increased symptoms from...

...Danial H. Shaikh; Haider Ghazanfar; Tegveer Sandhu; Ali Naqqi Ul Hussain; Harish Patel Kikuchi-Fujimoto disease (KFD), also known as histiocytic necrotizing lymphadenitis, is a rare, benign, focal, self-limiting disease. We report a unique case of KFD in a patient with coexisting Crohn’s disease...

...Gustavo Drügg Hahn; Panu Wetwittayakhlang; Waqqas Afif; Talat Bessissow; Peter L. Lakatos Crohn’s disease (CD) and Lynch syndrome (LS) are two different entities, yet both are associated with increased risk of colorectal cancer (CRC). We present the case of a young female patient in long-standing...

... the gastrointestinal problems started from infancy, and evolved to the development of Crohn’s disease, AIH, and PSC at a very early age. This case helps bring to light that very early onset autoimmune disorders may in fact present with symptoms of feeding difficulties, growth failure, and formula intolerance. Patients...

... disease Inflammatory bowel disease Case report Inflammatory bowel disease (IBD) is a chronic disease resulting from the interaction between genetic and environmental factors, which can affect the entire gastrointestinal tract. IBD is subdivided into Crohn’s disease and ulcerative colitis...

...Barrie Cohen; Gitit Tomer; Tatyana Gavrilova Ustekinumab is a monoclonal antibody used as treatment for various inflammatory conditions. We present a pediatric patient with Crohn’s disease who did not tolerate infliximab and was then changed to ustekinumab. He developed anaphylaxis...

...Mitra Barahimi; Scott Lee; Kindra Clark-Snustad We report the case of a 51-year-old male with Crohn’s disease (CD) who developed a reproducible pustular rash after ustekinumab (UST) administration. The patient first presented with a pustular rash on his hands, body, extremities, and scalp starting...

...Abeer S. Ali; Omar S. Alhothali; Abdulrahman A. Hammoudah; Abdullah Kh Alsaede; Ayman A. Alraddadi Crohn’s disease is a chronic inflammatory disease of the gastrointestinal tract with relapsing and remitting episodes. Abscesses and fistulas are the most common presentations of anorectal Crohn’s...

... with comprehensive stool microbial testing. In the setting of moderate-to-severe disease, patients on biologic therapy may be more prone to infectious complications. We present a patient with chronic Crohn’s disease with an unusual, previously undetected enteric infection due to Plesiomonas shigelloides. Once...