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Keywords: CDK4
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Journal Articles
Subject Area:
Gastroenterology
Case Rep Gastroenterol (2008) 1 (1): 7–14.
Published Online: 20 June 2007
... by amplified material of the 12q13–15 chromosomal region, present in the form of giant or ring chromosomes and leading to the overexpression of MDM2 and CDK4 genes. MDM2 and CDK4 proteins can be detected immunhistochemically, which was the case in the reported tumor. Overexpression of these proteins leads...