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1-20 of 246
Keywords: Streptococcus mutans
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Journal Articles
Streptococcus mutans GcrR Regulates Oral Biofilm from a Cariogenic State to a Non-Cariogenic State by Affecting Exopolysaccharide Production and Biofilm Homeostasis
Available to Purchase
Journal:
Caries Research
Caries Res (2025)
Published Online: 10 February 2025
...Bin Zhang; Anqi Zhang; Shihao Hou; Jielin Yang; Tao Hu; Yingming Yang; Lei Lei; Ruizhe Huang Introduction: Dental caries is a noncommunicable disease caused by dysbiosis of a dental biofilm. Streptococcus mutans is considered the major pathogen. The orphan response regulator GcrR negatively...
Journal Articles
Streptococcus mutans Gene Expression and Functional Profile in Root Caries: An RNA-Seq Study
Available to PurchaseHeitor Sales de Barros Santos, Thuy Do, Clarissa Cavalcanti Fatturi Parolo, Joice de Faria Poloni, Marisa Maltz, Rodrigo Alex Arthur, Nailê Damé-Teixeira
Journal:
Caries Research
Caries Res (2022) 56 (2): 116–128.
Published Online: 01 April 2022
...Heitor Sales de Barros Santos; Thuy Do; Clarissa Cavalcanti Fatturi Parolo; Joice de Faria Poloni; Marisa Maltz; Rodrigo Alex Arthur; Nailê Damé-Teixeira The literature is still scarce on studies describing Streptococcus mutans global gene expression under clinical conditions such as those found...
Journal Articles
The rnc Gene Regulates the Microstructure of Exopolysaccharide in the Biofilm of Streptococcus mutans through the β-Monosaccharides
Available to PurchaseYangyu Lu, Hongyu Zhang, Meng Li, Mengying Mao, Jiaqi Song, Yalan Deng, Lei Lei, Yingming Yang, Tao Hu
Journal:
Caries Research
Caries Res (2021) 55 (5): 534–545.
Published Online: 26 July 2021
...Yangyu Lu; Hongyu Zhang; Meng Li; Mengying Mao; Jiaqi Song; Yalan Deng; Lei Lei; Yingming Yang; Tao Hu Streptococcus mutans is known as the crucial pathogen of human dental caries, owing to its contribution to the biofilm development via the capacity of synthesizing exopolysaccharide (EPS), which...
Journal Articles
Journal:
Caries Research
Caries Res (2021) 55 (3): 205–214.
Published Online: 19 May 2021
... on bacterial aggregation, using monocultured planktonic cells of Streptococcus mutans and non-mutans streptococci. Coincubating S. mutans with EGCG (1 mg/mL) for 4 h had no bactericidal effects, while it decreased the growth and acid production of S. mutans by inhibiting the activity of the PEP-PTS. EGCG (2 mg...
Journal Articles
The pH-Responsive Property of Antimicrobial Peptide GH12 Enhances Its Anticaries Effects at Acidic pH
Available to Purchase
Journal:
Caries Research
Caries Res (2021) 55 (1): 21–31.
Published Online: 18 December 2020
... property of GH12 was determined to evaluate its potential as a smart acid-activated anticaries agent. GH12 possessed much lower minimal inhibitory concentrations and minimal bactericidal concentrations against various kinds of bacteria at pH 5.5 than at pH 7.2. Employing Streptococcus mutans...
Journal Articles
Effects of Sodium Trimetaphosphate, Associated or Not with Fluoride, on the Composition and pH of Mixed Biofilms, before and after Exposure to Sucrose
Available to PurchaseThamires Priscila Cavazana, Juliano Pelim Pessan, Thayse Yumi Hosida, Caio Sampaio, Viviane de Oliveira Zequini Amarante, Douglas Roberto Monteiro, Alberto Carlos Botazzo Delbem
Journal:
Caries Research
Caries Res (2020) 54 (4): 358–368.
Published Online: 30 September 2020
... or not with fluoride (F), on the concentrations of F, calcium (Ca), and phosphorus (P) and on the pH of mixed biofilms of Streptococcus mutans and Candida albicans , before and after exposure to sucrose. The biofilms received three treatments (72, 78, and 96 h after the beginning of their formation), at three TMP...
Journal Articles
Ahmad Zare Javid, Essam Amerian, Leila Basir, Alireza Ekrami, Mohammad Hosein Haghighizadeh, Leila Maghsoumi-Norouzabad
Journal:
Caries Research
Caries Res (2020) 54 (1): 68–74.
Published Online: 10 December 2019
... Bifidobacterium lactis Bb12 on salivary Streptococcus mutans and lactobacilli in students with initial stages of dental caries. In this double-blind randomized placebo-controlled clinical trial, 66 students (18–30 years) with initial stages of dental caries were selected and randomly assigned into 2 groups...
Journal Articles
Candida albicans Increases Dentine Demineralization Provoked by Streptococcus mutans Biofilm
Available to PurchaseAline A. Sampaio, Samilly E. Souza, Antônio P. Ricomini-Filho, Altair A. Del Bel Cury, Yuri W. Cavalcanti, Jaime A. Cury
Journal:
Caries Research
Caries Res (2019) 53 (3): 322–331.
Published Online: 16 November 2018
...Aline A. Sampaio; Samilly E. Souza; Antônio P. Ricomini-Filho; Altair A. Del Bel Cury; Yuri W. Cavalcanti; Jaime A. Cury Streptococcus mutans are considered the most cariogenic bacteria, but it has been suggested that Candida albicans could increase their cariogenicity. However, the effect...
Journal Articles
A Membrane-Targeted Peptide Inhibiting PtxA of Phosphotransferase System Blocks Streptococcus mutans
Available to Purchase
Journal:
Caries Research
Caries Res (2019) 53 (2): 176–193.
Published Online: 14 August 2018
...Shao-Wen Xiang; Jun Shao; Jian He; Xin-Yu Wu; Xiao-Hu Xu; Wang-Hong Zhao Streptococcus mutans , the primary cause of dental caries, takes up carbohydrates through the phosphoenolpyruvate sugar phosphotransferase system (PTS). This study aimed to identify a novel membrane-targeted antimicrobial...
Journal Articles
Effect of Bisphenol A Glycol Methacrylate on Virulent Properties of Streptococcus mutans UA159
Available to Purchase
Journal:
Caries Research
Caries Res (2019) 53 (1): 84–95.
Published Online: 29 June 2018
... materials. The purpose of this study was to investigate how bis-GMA changes the virulence properties of Streptococcus mutans , a major cariogenic bacterium in humans. The results show that bis-GMA not only inhibited the planktonic growth of cells in medium containing glucose, fructose, or mannose, but also...
Journal Articles
Cariogenicity of a Milk-Based Drink Used as a Dietary Supplement for Older Adults Using a Root Caries Experimental Model
Available to Purchase
Journal:
Caries Research
Caries Res (2019) 53 (1): 76–83.
Published Online: 26 June 2018
... a high concentration of sugars, which can contribute to root caries development. To test this hypothesis, an experimental biofilm/caries model was used. Dentin slabs were used to grow biofilms of Streptococcus mutans UA159. Slabs/biofilms were exposed 3× per day to bovine milk with different fat content...
Journal Articles
Fluoride Binding to Dental Biofilm Bacteria: Synergistic Effect with Calcium Questioned
Available to Purchase
Journal:
Caries Research
Caries Res (2019) 53 (1): 10–15.
Published Online: 06 June 2018
... concentrations (i.e., when CaF 2 precipitation may have occurred). We assessed fluoride binding to Streptococcus mutans pellets treated with calcium and fluoride at concentrations allowing CaF 2 precipitation or not. Increasing calcium concentration resulted in a linear increase ( p < 0.01) in fluoride...
Journal Articles
Phenalen-1-One-Mediated Antimicrobial Photodynamic Therapy and Chlorhexidine Applied to a Novel Caries Biofilm Model
Available to PurchaseFabian Cieplik, Fabian Wimmer, Denise Muehler, Thomas Thurnheer, Georgios N. Belibasakis, Karl-Anton Hiller, Tim Maisch, Wolfgang Buchalla
Journal:
Caries Research
Caries Res (2018) 52 (6): 447–453.
Published Online: 04 April 2018
... efficacy of aPDT with a phenalen-1-one photosensitizer was evaluated in a novel in vitro biofilm model comprising Actinomyces naeslundii , Actinomyces odontolyticus , and Streptococcus mutans and was compared to chlorhexidine. The proposed biofilm model allows high-throughput screening for antimicrobial...
Journal Articles
The Regulator Gene rnc Is Closely Involved in Biofilm Formation in Streptococcus mutans
Available to Purchase
Journal:
Caries Research
Caries Res (2018) 52 (5): 347–358.
Published Online: 06 March 2018
...Meng-Ying Mao; Meng Li; Lei Lei; Jia-Xin Yin; Ying-Ming Yang; Tao Hu Streptococcus mutans is an important factor in the etiology and pathogenesis of dental caries, largely owing to its ability to form a stable biofilm. Previous animal studies have indicated that rnc could decrease the amount...
Journal Articles
Microbiological Changes and Caries-Preventive Effect of an Innovative Varnish Containing Chlorhexidine in Orthodontic Patients
Available to Purchase
Journal:
Caries Research
Caries Res (2018) 52 (4): 272–278.
Published Online: 31 January 2018
... orthodontic appliance High-risk patients Lactobacilli Streptococcus mutans White spot lesions It has been shown that CHX is an antimicrobial agent which effectively helps to reduce the level of oral acidic bacteria and consequently the demineralization of the tooth surfaces in different studies...
Journal Articles
Analysis of the Cariogenic Potential of Various Almond Milk Beverages using a Streptococcus mutans Biofilm Model in vitro
Available to PurchaseJanelle Lee, Janice A. Townsend, Tatyana Thompson, Thomas Garitty, Arpan De, Qingzhao Yu, Brian M. Peters, Zezhang T. Wen
Journal:
Caries Research
Caries Res (2018) 52 (1-2): 51–57.
Published Online: 15 December 2017
... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Almond milk Cariogenicity Dental caries Streptococcus mutans Bovine milk alternative beverages are on the rise. Among those available...
Journal Articles
Streptococcus mutans in Mother-Child Dyads and Early Childhood Caries: Examining Factors Underlying Bacterial Colonization
Available to PurchaseElizabeth L. Costa, José F. Costa, Matheus P. Santos, Lorena L.C. Ladeira, Rubenice A. Silva, Cecília C.C. Ribeiro
Journal:
Caries Research
Caries Res (2018) 51 (6): 582–589.
Published Online: 21 October 2017
...Elizabeth L. Costa; José F. Costa; Matheus P. Santos; Lorena L.C. Ladeira; Rubenice A. Silva; Cecília C.C. Ribeiro This study investigated the association between colonization of mother-child dyads with Streptococcus mutans (SM) and early childhood caries (ECC), with consideration of the mediator...
Journal Articles
The in vivo Inhibition of Oral Biofilm Accumulation and Streptococcus mutans by Ceramic Water
Available to PurchaseRyota Nomura, Risa Yoneyama, Shuhei Naka, Masatoshi Otsugu, Yuko Ogaya, Rina Hatakeyama, Yumiko Morita, Jumpei Maruo, Michiyo Matsumoto-Nakano, Osamu Yamada, Kazuhiko Nakano
Journal:
Caries Research
Caries Res (2017) 51 (1): 58–67.
Published Online: 22 December 2016
... in water. This generates antimicrobial activity against various bacteria. One such bacterium is Streptococcus mutans , a gram-positive anaerobic bacterium known as a major pathogen of dental caries. In this study, we analyzed the inhibition of oral biofilms and S. mutans by ceramic water in in vitro...
Journal Articles
Analysis of Bacterial Activity in Sound and Cariogenic Biofilm: A Pilot in vivo Study
Available to PurchaseKarsten Henne, Antonia-Patricia Gunesch, Carolin Walther, Hendrik Meyer-Lueckel, Georg Conrads, Marcella Esteves-Oliveira
Journal:
Caries Research
Caries Res (2016) 50 (5): 480–488.
Published Online: 06 September 2016
... donor sites: a cavitated lesion with an ICDAS score of 5-6 (CAC, n = 13), and a sound reference surface (CAS, n = 13). Four aciduric/acidogenic bacterial taxa (Streptococcus mutans, lactobacilli , Bifidobacterium dentium, and Scardovia wiggsiae) and one asaccharolytic taxon (fusobacteria) as a contrast...
Journal Articles
Insights into the Virulence Traits of Streptococcus mutans in Dentine Carious Lesions of Children with Early Childhood Caries
Available to PurchaseDaniela S. Bezerra, Rafael N. Stipp, Beatriz G. Neves, Sarah F.F. Guedes, Marcelle M. Nascimento, Lidiany K.A. Rodrigues
Journal:
Caries Research
Caries Res (2016) 50 (3): 279–287.
Published Online: 03 May 2016
...Daniela S. Bezerra; Rafael N. Stipp; Beatriz G. Neves; Sarah F.F. Guedes; Marcelle M. Nascimento; Lidiany K.A. Rodrigues Streptococcus mutans is an oral bacterium considered to play a major role in the development of dental caries. This study aimed to investigate the prevalence of S. mutans...
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