...Bin Zhang; Anqi Zhang; Shihao Hou; Jielin Yang; Tao Hu; Yingming Yang; Lei Lei; Ruizhe Huang Introduction: Dental caries is a noncommunicable disease caused by dysbiosis of a dental biofilm. Streptococcus mutans is considered the major pathogen. The orphan response regulator GcrR negatively...

...Heitor Sales de Barros Santos; Thuy Do; Clarissa Cavalcanti Fatturi Parolo; Joice de Faria Poloni; Marisa Maltz; Rodrigo Alex Arthur; Nailê Damé-Teixeira The literature is still scarce on studies describing Streptococcus mutans global gene expression under clinical conditions such as those found...

...Yangyu Lu; Hongyu Zhang; Meng Li; Mengying Mao; Jiaqi Song; Yalan Deng; Lei Lei; Yingming Yang; Tao Hu Streptococcus mutans is known as the crucial pathogen of human dental caries, owing to its contribution to the biofilm development via the capacity of synthesizing exopolysaccharide (EPS), which...

... on bacterial aggregation, using monocultured planktonic cells of Streptococcus mutans and non-mutans streptococci. Coincubating S. mutans with EGCG (1 mg/mL) for 4 h had no bactericidal effects, while it decreased the growth and acid production of S. mutans by inhibiting the activity of the PEP-PTS. EGCG (2 mg...

... property of GH12 was determined to evaluate its potential as a smart acid-activated anticaries agent. GH12 possessed much lower minimal inhibitory concentrations and minimal bactericidal concentrations against various kinds of bacteria at pH 5.5 than at pH 7.2. Employing Streptococcus mutans...

... or not with fluoride (F), on the concentrations of F, calcium (Ca), and phosphorus (P) and on the pH of mixed biofilms of Streptococcus mutans and Candida albicans , before and after exposure to sucrose. The biofilms received three treatments (72, 78, and 96 h after the beginning of their formation), at three TMP...

... Bifidobacterium lactis Bb12 on salivary Streptococcus mutans and lactobacilli in students with initial stages of dental caries. In this double-blind randomized placebo-controlled clinical trial, 66 students (18–30 years) with initial stages of dental caries were selected and randomly assigned into 2 groups...

...Aline A. Sampaio; Samilly E. Souza; Antônio P. Ricomini-Filho; Altair A. Del Bel Cury; Yuri W. Cavalcanti; Jaime A. Cury Streptococcus mutans are considered the most cariogenic bacteria, but it has been suggested that Candida albicans could increase their cariogenicity. However, the effect...

...Shao-Wen Xiang; Jun Shao; Jian He; Xin-Yu Wu; Xiao-Hu Xu; Wang-Hong Zhao Streptococcus mutans , the primary cause of dental caries, takes up carbohydrates through the phosphoenolpyruvate sugar phosphotransferase system (PTS). This study aimed to identify a novel membrane-targeted antimicrobial...

... materials. The purpose of this study was to investigate how bis-GMA changes the virulence properties of Streptococcus mutans , a major cariogenic bacterium in humans. The results show that bis-GMA not only inhibited the planktonic growth of cells in medium containing glucose, fructose, or mannose, but also...

... a high concentration of sugars, which can contribute to root caries development. To test this hypothesis, an experimental biofilm/caries model was used. Dentin slabs were used to grow biofilms of Streptococcus mutans UA159. Slabs/biofilms were exposed 3× per day to bovine milk with different fat content...

... concentrations (i.e., when CaF 2 precipitation may have occurred). We assessed fluoride binding to Streptococcus mutans pellets treated with calcium and fluoride at concentrations allowing CaF 2 precipitation or not. Increasing calcium concentration resulted in a linear increase ( p < 0.01) in fluoride...

... efficacy of aPDT with a phenalen-1-one photosensitizer was evaluated in a novel in vitro biofilm model comprising Actinomyces naeslundii , Actinomyces odontolyticus , and Streptococcus mutans and was compared to chlorhexidine. The proposed biofilm model allows high-throughput screening for antimicrobial...

...Meng-Ying Mao; Meng Li; Lei Lei; Jia-Xin Yin; Ying-Ming Yang; Tao Hu Streptococcus mutans is an important factor in the etiology and pathogenesis of dental caries, largely owing to its ability to form a stable biofilm. Previous animal studies have indicated that rnc could decrease the amount...

... orthodontic appliance High-risk patients Lactobacilli Streptococcus mutans White spot lesions It has been shown that CHX is an antimicrobial agent which effectively helps to reduce the level of oral acidic bacteria and consequently the demineralization of the tooth surfaces in different studies...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Almond milk Cariogenicity Dental caries Streptococcus mutans Bovine milk alternative beverages are on the rise. Among those available...

...Elizabeth L. Costa; José F. Costa; Matheus P. Santos; Lorena L.C. Ladeira; Rubenice A. Silva; Cecília C.C. Ribeiro This study investigated the association between colonization of mother-child dyads with Streptococcus mutans (SM) and early childhood caries (ECC), with consideration of the mediator...

... in water. This generates antimicrobial activity against various bacteria. One such bacterium is Streptococcus mutans , a gram-positive anaerobic bacterium known as a major pathogen of dental caries. In this study, we analyzed the inhibition of oral biofilms and S. mutans by ceramic water in in vitro...

... donor sites: a cavitated lesion with an ICDAS score of 5-6 (CAC, n = 13), and a sound reference surface (CAS, n = 13). Four aciduric/acidogenic bacterial taxa (Streptococcus mutans, lactobacilli , Bifidobacterium dentium, and Scardovia wiggsiae) and one asaccharolytic taxon (fusobacteria) as a contrast...

...Daniela S. Bezerra; Rafael N. Stipp; Beatriz G. Neves; Sarah F.F. Guedes; Marcelle M. Nascimento; Lidiany K.A. Rodrigues Streptococcus mutans is an oral bacterium considered to play a major role in the development of dental caries. This study aimed to investigate the prevalence of S. mutans...