...Marwa M. Alhothali; Rob A.M. Exterkate; Maxim D. Lagerweij; A.J.P. van Strijp; Mark J. Buijs; Cor van Loveren This study compared the effect of topically applied fluoride products on dentine lesions in an in vitro experiment. Demineralized bovine dentine specimens were treated once with either SDF...

...Cheryl Ann Miller; Eleanor Ashworth; Chris Deery; Lamis El sharkasi; Robert David Moorehead; Nicolas Martin There is a requirement to ensure that in vitro studies that use demineralized human dentine models are reliable and clinically relevant. The literature reports several strategies...

...Daiana Moreli Soares dos Santos; Juliana Gonçalves Pires; Aline Braga Silva; Priscila Maria Aranda Salomão; Marília Afonso Rabelo Buzalaf; Ana Carolina Magalhães This study evaluated the effect of titanium tetrafluoride (TiF 4 ) varnish on the development of dentin carious lesions. Bovine root...

... to evaluate if starch combined with sucrose provokes higher root dentine demineralization than sucrose alone. Biofilms ( n = 18) composed by Streptococcus mutans (the most cariogenic bacteria), Actinomces naeslundii (which has amylolytic activity), and Streptococcus gordonii (which binds salivary amylase...

...Nadine Schlueter; Katja Jung; Carolina Ganss Profilometry is established in erosion research. However, in the case of dentine, factors such as the demineralised organic matrix, desiccation effects, or type of measuring device may have an impact on the measurement results, which were investigated...

... of different fluoride concentrations and the time of application (before/after erosive challenge). Bovine enamel (n = 15/group) and root dentine (n = 12/group) specimens were submitted to the following treatments: after the first erosive challenge - 0.9% NaCl solution (negative control), whole milk with 0, 2.5...

... phosphopeptide-amorphous calcium phosphate, 0.2% NaF), F (0.2% NaF) and placebo. Two-hundred and forty enamel and 240 dentine specimens were selected by using surface microhardness; half of them were subjected to pre-demineralisation and the other half remained sound. Sound specimens were further exposed...

... ppm Sn 2+ ), and the impact of the demineralised dentine matrix on toothpaste effects. The study was a cyclic erosion/intervention experiment (10 days). Samples were stored in mineral salt solution either without or with collagenase (from Clostridium histolyticum type VII; 100 U/ml) for continuous...

...B.M. Moron; L.P. Comar; A. Wiegand; W. Buchalla; H. Yu; M.A.R. Buzalaf; A.C. Magalhães This study compared dentine demineralization induced by in vitro and in situ models, and correlated dentine surface hardness (SH), cross-sectional hardness (CSH) and mineral content by transverse microradiography...

...A. Almahdy; F.C. Downey; S. Sauro; R.J. Cook; M. Sherriff; D. Richards; T.F. Watson; A. Banerjee; F. Festy The aim of this study was to evaluate and correlate objectively the microspectroscopically derived biochemical components of sound, infected and affected carious dentine...

...M.F. Correia; L.M.A. Tenuta; A.A. Del Bel Cury; J.A. Cury To test the effect of distinct solubilities of dentine and enamel on mineral ion concentration in the biofilm fluid during a sugar-induced pH drop, dental biofilms were formed in situ for 4 days on acrylic (control), dentine or enamel...

...P.G. Spizzirri; N.J. Cochrane; S. Prawer; E.C. Reynolds Carbonate determination in dental apatites such as dentine and enamel is important for studying the dynamics of dental caries and developmental defects of these tissues. Traditionally, these determinations have been performed by acidic...

...M. Toledano; M. Yamauti; E. Osorio; R. Osorio Background: Dentine matrix metalloproteinases (MMPs) play an important role in the dentine caries process. Aims: To determine if MMP-mediated collagen degradation of acid-demineralized dentine may be inhibited by zinc or zinc chelators. Methods: Human...

...N. Schlueter; A. Hara; R.P. Shellis; C. Ganss The advantages, limitations and potential applications of available methods for studying erosion of enamel and dentine are reviewed. Special emphasis is placed on the influence of histological differences between the dental hard tissue and the stage...

.... In the process of dental erosion, the initial acid attacks on the tooth surface result in a superficial partial dissolution of mineral – early-stage surface softening [Arends and Ten Cate, 1981] – which can reach a few micrometres into enamel or dentine [Imfeld, 1996; Finke et al., 2000; Addy and Shellis, 2006...

... factors and interactions with pH need to be taken into account when developing multivariate models for predicting the erosive potential of different solutions. Finally, the erosive potential of solutions towards enamel and dentine might differ. pH-stat Profilometry Soft drinks Nanohardness...

...M.T. Kato; A.R. Hannas; A.L. Leite; A. Bolanho; B.L. Zarella; J. Santos; M. Carrilho; L. Tjäderhane; M.A.R. Buzalaf Metalloproteinases (MMPs) have been implicated with metabolism of collagen in physiological and pathological processes in human dentine. As bovine teeth have been used as a substitute...

...A.J. Smith The dentine-pulp complex shows a broad spectrum of responses to caries of the dental tissues, which represents a summation of injury, defence and repair events taking place. The relative importance of these various events will reflect both the extent of disease activity and metabolic...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Caries Dentine In vitro Solubility Original Paper Caries Res...

... might influence dentine erosion. Based on this, the aims of this study were: (1) to test in vitro the effect of FeSO 4 on MMP-2 and -9 activity, and (2) to evaluate in situ the effect of FeSO 4 gel on dentine erosion. MMP-2 and -9 activities were analysed zymographically in buffers containing FeSO 4...