... cariogenesis. To meet this challenge, we designed C16G2, a novel synthetic specifically targeted antimicrobial peptide with specificity for S. mutans . C16G2 consists of a S. mutans -selective ‘targeting region’ comprised of a fragment from S. mutans competence stimulation peptide (CSP) conjoined to a ‘killing...

... generally had a lower activity with a minimum MIC of 2 mg ml –1 for tea extracts, grape seed extracts and Pynogenol® (extract of maritime pine). All other extracts had MICs of ≧4 mg ml –1 . Unfermented cocoa had greater antimicrobial activity than fermented cocoa and the activity of the fractionated extract...