In São Paulo, Brazil, 566 children, 14–17 years old, completed a 3-year study to evaluate the anticaries effect of self-applications of acidulated phosphate fluoride (APF). There were five study groups: group A (controls) brushed with a non-fluoride prophylaxis paste and then with a placebo solution; group B brushed with the paste and then with an APF solution (0.6% F, pH 3); group C brushed with the APF solution without brushing first with the paste; group D brushed with the paste and then with an APF gel (1.23% F, pH 3); and group E brushed with the APF gel without brushing first with the paste. Fifteen brushings spaced evenly during 3 school years were made in school, supervised by lay personnel. After three years, there were reductions in incremental DMF surfaces of 26, 26, 33 and 19% in groups B, C, D and E, respectively, compared with controls. The differences in all treatment groups from controls, with exception of that in group E, were significant at the 0.05 level.

Keywords:
Caries, Cleansing of teeth, Clinical trial, Fluoride, topical, Phosphate fluoride
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© 1974 S. Karger AG, Basel
1974
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