The purpose of this study was to improve the sensitivity of the biopsy method developed by Brudevold et al. Enamel surfaces were abraded by means of rubber cups and silicon carbide. The slurry was collected by the lip of the cup, which was cut off and transferred to a plastic test tube. The material was dissolved in perchloric acid and buffered by sodium citrate. Fluoride was determined by a combination fluoride activity electrode and calcium by atomic absorption spectrophotometry. The method permits determination of the fluoride content in approximately 0.2-μm thick layers within single tooth surfaces. In two selected groups of 207 children (7–16 years of age) residing in high and low fluoride areas, the fluoride concentration in the enamel surface ranged from 1,000 to 6,000 ppm. In 33 children two successive layers were sampled, each being approximately 0.5 μm thick. In the first layer the fluoride concentration ranged from 2,000 to 5,800 ppm and in the second from 1,500 to 4,800 ppm.

This content is only available via PDF.
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.