The anticaries effects of topically-applied NaF and SnF2 solutions and of a SnF2 dentifrice were compared under a wide variety of experimental conditions in rats. The parameters examined included: concentration of fluoride, frequency of application of fluoride, age of animal, duration of study and extent of lesion formation. The anticaries efficacy of fluoride (SnF2 or NaF) was significantly increased as the concentration of fluoride and the frequency of application were increased. No consistent superiority was found for one compound (SnF2 versus NaF) over the experimental conditions studied. The age of the animal, duration of study and extent of lesion formation did not significantly alter the relative efficacies of SnF2 and NaF.

This content is only available via PDF.
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.