A description is presented of a method for tube-feeding solutions to newborn rats on a daily basis. The technique is quick, accurate, simple, reasonably safe and without apparent effect on the health, growth rate or caries-susceptibility of the rats. Newborn rats were randomly allocated to groups receiving twice daily doses of 10-per cent solutions of sucrose or lactose or distilled water by stomachtube up to 17 days of age. Subsequently, all the rats were fed the same caries-producing diets until they were killed at 81 days of age. No significant differences between the caries susceptibilities of the groups could be discovered.

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