The aim of this paper was to investigate associations between the intake of dairy products and the development in caries (DMFS, decayed, missing and filled surfaces) among children/adolescents over a period of 3 and 6 years, and to investigate whether dairy intake protects against caries incidence. A total of 68.9% of the children were caries free at the age of 9 compared with 34.0% of the adolescents at the age of 15 (measured as DMFS = 0). A larger percentage of children/adolescents with a dairy intake above the mean were caries free compared with the group of children/adolescents with an intake below the mean (72.8 vs. 65.8% at age 9 and 41.1 vs. 30.7% at age 15). The results from the generalized estimation equation showed that dairy and milk intake, as well as intakes of components of dairy such as dairy calcium, whey and casein, was generally inversely associated with childhood/adolescent caries experience (measured as DMFS). With regard to caries incidence, the same inverse association was found for incidence over a period of 3 years and for incidence over 6 years, but the results were only statistically significant for the 3-year incidence and for the unadjusted models of the 6-year incidence. This study found that previous dairy intake, as well as milk intake or intake of dairy components, may be a predictor of future risk of caries measured by the DMFS count level. This relationship was inverse, meaning that a high intake of dairy products was associated with less future caries development. However, more studies on larger cohorts are needed to confirm these findings.

Keywords:
Dairy, Milk, Calcium, Whey, Casein, Childhood, Caries, DMFS, European Youth Heart Study
1.
Altman DG: Practical Statistics for Medical Research. London, Capman & Hall 1991, vol 247-48, pp 316-318, 337.
2.
Azarpazhooh A, Limeback H: Clinical efficacy of casein derivatives: a systematic review of the literature. J Am Dent Assoc 2008;139:915-924, quiz 994-925.
3.
Bachman CM, Baranowski T, Nicklas TA: Is there an association between sweetened beverages and adiposity? Nutr Rev 2006;64:153-174.
4.
Beck AM, Hoppe C, Ygil KH, Andersen NL, Pedersen AN: Vidensgrundlag for rådgivning om indtag af mælk, mælkeprodukter og ost i Danmark. Technical University of Denmark, DTU, 2010.
5.
Caglar E, Kuscu OO, Selvi Kuvvetli S, Kavaloglu Cildir S, Sandalli N, et al: Short-term effect of ice-cream containing Bifidobacterium lactis Bb-12 on the number of salivary mutans streptococci and lactobacilli. Acta Odontol Scand 2008;66:154-158.
6.
Caglar E, Sandalli N, Twetman S, Kavaloglu S, Ergeneli S, et al: Effect of yogurt with Bifidobacterium DN-173 010 on salivary mutans streptococci and lactobacilli in young adults. Acta Odontol Scand 2005;63:317-320.
7.
Cameron FL, Weaver LT, Wright CM, Welbury RR: Dietary and social characteristics of children with severe tooth decay. Scott Med J 2006;51:26-29.
8.
Christensen LB, Petersen PE, Hede B: Oral health in children in Denmark under different public dental health care schemes. Community Dent Health 2010a;27:94-101.
9.
Christensen LB, Twetman S, Sundby A: Oral health in children and adolescents with different socio-cultural and socio-economic backgrounds. Acta Odontol Scand 2010b;68:34-42.
10.
Cinar AB, Christensen LB, Hede B: Clustering of obesity and dental caries with lifestyle factors among Danish adolescents. Oral Health Prev Dent 2011;9:123-130.
11.
Glavina D, Gorseta K, Skrinjaric I, Vranic DN, Mehulic K, et al: Effect of LGG yoghurt on Streptococcus mutans and Lactobacillus spp. salivary counts in children. Coll Antropol 2012;36:129-132.
12.
Hausen H, Karkkainen S, Seppa L: Caries data collected from public health records compared with data based on examinations by trained examiners. Caries Res 2001;35:360-365.
13.
Helm S: Recording system for the Danish Child Dental Health Services. Community Dent Oral Epidemiol 1973;1:3-8.
14.
Johansson I, Lif Holgerson P: Milk and oral health. Nestle Nutr Workshop Ser Pediatr Program 2011;67:55-66.
15.
Kõll-Klais P, Mändar R, Leibur E, Marcotte H, Hammarström L, et al: Oral lactobacilli in chronic periodontitis and periodontal health: species composition and antimicrobial activity. Oral Microbiol Immunol 2005;20:354-361.
16.
Lawless J: Negative binomial and mixed Poisson regression. Can J Stat 1987;15:209-225.
17.
Lexner MO, Blomqvist S, Dahlén G, Twetman S: Microbiological profiles in saliva and supragingival plaque from caries-active adolescents before and after a short-term daily intake of milk supplemented with probiotic bacteria - a pilot study. Oral Health Prev Dent 2010;8:383-388.
18.
Liang KY, Zenger SL: Longitudinal data analysis using generalized linear models. Biometrika 1986;73:13-22.
19.
Lingström P, Holm A, Mejàre I, Twetman S, Söder B, et al: Dietary factors in the prevention of dental caries: a systematic review. Acta Odontol Scand 2003;61:331-340.
20.
Llena C, Forner L, Baca P: Anticariogenicity of casein phosphopeptide-amorphous calcium phosphate: a review of the literature. J Contemp Dent Pract 2009;10:1-9.
21.
Marshall TA, Eichenberger-Gilmore JM, Broffitt BA, Warren JJ, Levy SM: Dental caries and childhood obesity: roles of diet and socioeconomic status. Community Dent Oral Epidemiol 2007;35:449-458.
22.
Merchant AT, Pitiphat W: Directed acyclic graphs (DAGs): an aid to assess confounding in dental research. Community Dent Oral Epidemiol 2002;30:399-404.
23.
Mobley CC: Nutrition and dental caries. Dent Clin North Am 2003;47:319-336.
24.
Nicolau B, Marcenes W, Bartley M, Sheiham A: A life course approach to assessing causes of dental caries experience: the relationship between biological, behavioural, socio-economic and psychological conditions and caries in adolescents. Caries Res 2003;37:319-326.
25.
Nielsen BM, Bjornsbo KS, Tetens I, Heitmann BL: Dietary glycaemic index and glycaemic load in Danish children in relation to body fatness. Br J Nutr 2005;94:992-997.
26.
NNR: Nordic Nutrition Recommendations, ed 4. 2004.
27.
Petersen PE: The World Oral Health Report 2003: continuous improvement of oral health in the 21st century - the approach of the WHO Global Oral Health Programme. Community Dent Oral Epidemiol 2003;31(suppl 1):3-23.
28.
Riddoch C, Edwards D, Page A, Froberg K, Anderssen SA, et al: European Youth Heart Study background. World Wide Web 2000, pp 1-23. http://www.enshe.lu/committees/children/background.pdf (accessed May 4, 2003).
29.
Riddoch C, Edwards D, Page A, Froberg K, Anderssen S, et al: The European Youth Heart Study - cardiovascular disease risk factors in children: rationale, aims, study design, and validation of methods. J Phys Act Health 2005;2:115-129.
30.
Séverin S, Wenshui X: Milk biologically active components as nutraceuticals: review. Crit Rev Food Sci Nutr 2005;45:645-656.
31.
Sheiham A: Dietary effects on dental diseases. Public Health Nutr 2001;4:569-591.
32.
Stecksén-Blicks C, Sjöström I, Twetman S: Effect of long-term consumption of milk supplemented with probiotic lactobacilli and fluoride on dental caries and general health in preschool children: a cluster-randomized study. Caries Res 2009;43:374-381.
33.
Tanaka K, Miyake Y, Sasaki S: Intake of dairy products and the prevalence of dental caries in young children. J Dent 2010;38:579-583.
34.
Twetman L, Larsen U, Fiehn N, Stecksen-Blicks C, Twetman S: Coaggregation between probiotic bacteria and caries-associated strains: an in vitro study. Acta Odontol Scand 2009;67:284-288.
35.
Twetman S, Keller MK: Probiotics for caries prevention and control. Adv Dent Res 2012;24:98-102.
36.
Twetman S, Stecksén-Blicks C: Probiotics and oral health effects in children. Int J Paediatr Dent 2008;18:3-10.
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