The aim of this study was to investigate the relationship between several parameters of saliva and erosive wear in adolescents. (Un-)stimulated saliva was collected from 88 adolescents with erosion and 49 controls (age 16 ± 1 years). Flow rate, pH and buffer capacity were determined immediately. Total protein content, carbonic anhydrase VI, amylase, albumin, calcium, phosphate, urea, sodium, chloride and potassium were measured at a later time. Unstimulated flow rate was found to be significantly lower in subjects with erosive wear (p = 0.016). The chloride concentration in unstimulated saliva was found to be significantly higher in the erosion group (p = 0.019).

Bardow A, Moe D, Nyvad B, Nauntofte B: The buffer capacity and buffer systems of human whole saliva measured without loss of CO2. Arch Oral Biol 2000;45:1-12.
El Aidi H, Bronkhorst EM, Huysmans MC, Truin GJ: Multifactorial analysis of factors associated with the incidence and progression of erosive tooth wear. Caries Res 2011;45:303-312.
El Aidi H, Bronkhorst EM, Huysmans MCDNJM, Truin GJ: Dynamics of tooth erosion in adolescents: a 3-year longitudinal study. J Dent 2010;38:131-137.
Ferguson DB, Fort A, Elliot AL, Potts AJ: Circadian rhythms in human parotid saliva flow rate and composition. Arch Oral Biol 1973;18:1155-1173.
Hannig M, Joiner A: The structure, function and properties of the acquired pellicle. Monogr Oral Sci 2006;19:29-64.
Humphrey SP, Williamson RT: A review of saliva: normal composition, flow and function. J Prosthet Dent 2001;85:162-169.
Jaeggi T, Lussi A: Prevalence, incidence and distribution of erosion. Monogr Oral Sci 2006;20:44-65.
Jager DHJ, Vieira AM, Ligtenberg AJM, Bronkhorst EM, Huysmans MCDNJM, Vissink A: The effect of saliva on the susceptibility of hydroxyapatite to erosion. Caries Res 2011;45:532-537.
Järvinen VK, Rytömaa II, Heinonen OP: Risk factors in dental erosion in children. J Dent Res 1991;70:942-947.
Johansson AK, Lingström P, Birkhed D: Comparison of factors potentially related to the occurrence of dental erosion in high- and low-erosion groups. Eur J Oral Sci 2002;110:204-211.
Kandori K, Masunari A, Ishikawa T: Study of adsorption mechanism of proteins onto synthetic calcium hydroxyapatites through ionic concentration measurements. Calcif Tissue Int 2005;76:194-206.
Kato MT, Lancia M, Sales-Peres SH, Buzalaf MA: Preventive effect of commercial desensitizing toothpastes on bovine enamel erosion in vitro. Caries Res 2010;44:85-89.
Kielbassa AM, Oeschger U, Schulte-Monting J, Meyer-Lueckel H: Microradiographic study on the effects of salivary proteins on in vitro demineralization of bovine enamel. J Oral Rehabil 2005;32:90-96.
Kwon KY, Wang E, Chung A, Chang N, Lee SW: Effect of salinity on hydroxyapatite dissolution studied by atomic force microscopy. J Phys Chem C 2009;113:3369-3372.
Leinonen J, Kivelä J, Parkkila S, Parkkila AK, Rajaniemi H: Salivary carbonic anhydrase isoenzyme VI is located in the human enamel pellicle. Caries Res 1999;33:185-190.
Lubarsky GV, D'Sa RA, Deb S, Meenan BJ, Lemoine P: The role of enamel proteins in protecting mature human enamel against acidic environments: a double layer force spectroscopy study. Biointerphases 2012;7:14.
Lussi A: Dental erosion clinical diagnosis and case history taking. Eur J Oral Sci 1996;104:191-198.
Murakami H, Sly WS: Purification and characterization of human salivary carbonic anhydrase. J Biol Chem 1987;262:1382-1388.
Nieuw Amerongen A: Speekel, speekselklieren en mondgezondheid. Houten, Bohn Stafleu van Loghum, 2004.
O'Sullivan EA, Curzon MEJ: Salivary factors affecting dental erosion in children. Caries Res 2000;34:82-87.
Schipper RG, Silletti E, Vingerhoeds MH: Saliva as research material: biochemical, physiochemical and practical aspects. Arch Oral Biol 2007;52:1114-1135.
van Rijkom HM, Truin GJ, Frencken JEFM, König KG, van 't Hof MA, Bronkhorst EM, Roeters FJM: Prevalence, distribution and background variables of smooth-bordered tooth wear in teenagers in The Hague, The Netherlands. Caries Res 2002;36:147-154.
Wetton S, Hughes J, Newcombe RG, Addy M: The effect of saliva derived from different individuals on the erosion of enamel and dentine: a study in vitro. Caries Res 2007;41:323-327.
White AJ, Jones SB, Barbour ME, Churchley DR, Gracia LH, Rees GD: Inhibition of erosive dissolution by sodium fluoride: evidence for a dose-response. J Dent 2012;40:654-660.
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