This study evaluated the influence of the penetration coefficient (PC) and ethanol addition on the penetration depth (PD) of experimental infiltrants into proximal caries lesions in primary molars. Caries lesions (n = 45) were randomly treated with 1 of 4 experimental infiltrants (PC63; PC185; PC204; PC391) for 5 min. Lesion depths and PDs were analysed using dual fluorescence confocal microscopy. Lesions were almost completely infiltrated in all groups. Median PDs and percentage penetrations were not significantly different between groups (p > 0.05). When applied for 5 min, all tested infiltrants were able to infiltrate proximal caries in primary molars nearly completely.

Ekstrand KR, Bakhshandeh A, Martignon S: Treatment of proximal superficial caries lesions on primary molar teeth with resin infiltration and fluoride varnish versus fluoride varnish only: efficacy after 1 year. Caries Res 2010;44:41–46.
Fan PL, Seluk LW, O’Brien WJ: Penetrativity of sealants. Part I. J Dent Res 1975;54:262–264.
Griffin SO, Oong E, Kohn W, Vidakovic B, Gooch BF, Bader J, Clarkson J, Fontana MR, Meyer DM, Rozier RG, Weintraub JA, Zero DT, Group CDSSRW: The effectiveness of sealants in managing caries lesions. J Dent Res 2008;87:169–174.
Holmen L, Thylstrup A, Ogaard B, Kragh F: A polarized light microscopic study of progressive stages of enamel caries in vivo. Caries Res 1985;19:348–354.
Ismail AI, Sohn W, Tellez M, Amaya A, Sen A, Hasson H, Pitts NB: The international caries detection and assessment system (ICDAS): an integrated system for measuring dental caries. Community Dent Oral Epidemiol 2007;35:170–178.
Lindén LA, Björkman S, Hattab F: The diffusion in vitro of fluoride and chlorhexidine in the enamel of human deciduous and permanent teeth. Arch Oral Biol 1986;31:33–37.
Llodra JC, Bravo M, Delgado-Rodriguez M, Baca P, Galvez R: Factors influencing the effectiveness of sealants – a meta-analysis. Community Dent Oral Epidemiol 1993;21:261–268.
Martignon S, Ekstrand KR, Ellwood R: Efficacy of sealing proximal early active lesions: an 18-month clinical study evaluated by conventional and subtraction radiography. Caries Res 2006;40:382–388.
Meyer-Lueckel H, Paris S: Improved resin infiltration of natural caries lesions. J Dent Res 2008a;87:1112–1116.
Meyer-Lueckel H, Paris S: Progression of artificial enamel caries lesions after infiltration with experimental light curing resins. Caries Res 2008b;42:117–124.
Meyer-Lueckel H, Paris S: Infiltration of natural caries lesions with experimental resins differing in penetration coefficients and ethanol addition. Caries Res 2010;44:408–414.
Meyer-Lueckel H, Paris S, Kielbassa AM: Surface layer erosion of natural caries lesions with phosphoric and hydrochloric acid gels in preparation for resin infiltration. Caries Res 2007;41:223–230.
Mortimer KV: The relationship of deciduous enamel structure to dental disease. Caries Res 1970;4:206–223.
Paris S, Bitter K, Renz H, Hopfenmuller W, Meyer-Lueckel H: Validation of two dual fluorescence techniques for confocal microscopic visualization of resin penetration into enamel caries lesions. Microsc Res Tech 2009;72:489–494.
Paris S, Dörfer CE, Meyer-Lueckel H: Surface conditioning of natural enamel caries lesions in deciduous teeth in preparation for resin infiltration. J Dent 2010a;38:65–71.
Paris S, Hopfenmuller W, Meyer-Lueckel H: Resin infiltration of caries lesions: an efficacy randomized trial. J Dent Res 2010b;89:823–826.
Paris S, Meyer-Lueckel H, Cölfen H, Kielbassa AM: Resin infiltration of artificial enamel caries lesions with experimental light curing resins. Dent Mater J 2007a;26:582–588.
Paris S, Meyer-Lueckel H, Kielbassa AM: Resin infiltration of natural caries lesions. J Dent Res 2007b;86:662–666.
Paris S, Soviero VM, Seddig S, Meyer-Lueckel H: Penetration depths of an infiltrant into proximal caries lesions in primary molars after different application times in vitro. Int J Paediatr Dent 2011, E-pub ahead of print.
Pashley DH, Tay FR, Breschi L, Tjäderhane L, Carvalho RM, Carrilho M, Tezvergil-Mutluay A: State of the art etch-and-rinse adhesives. Dent Mater 2011;27:1–16.
Simonsen RJ: Pit and fissure sealant: review of the literature. Pediatr Dent 2002;24:393–414.
Ye Q, Spencer P, Wang Y, Misra A: Relationship of solvent to the photopolymerization process, properties, and structure in model dentin adhesives. J Biomed Mater Res A 2007;80:342–350.
Yiu CK, Pashley EL, Hiraishi N, King NM, Goracci C, Ferrari M, Carvalho RM, Pashley DH, Tay FR: Solvent and water retention in dental adhesive blends after evaporation. Biomaterials 2005;26:6863–6872.
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.