The aim of this study was to determine if saliva from 14 subjects afforded different levels of protection to human enamel and dentine against erosion in vitro. Test specimens were exposed for 2 h to saliva and control specimens to water for 2 h followed by citric acid for 10 min. This cycle was carried out 12 times. Tissue loss measured by contact profilometry was highly significantly different between subjects. Erosion was significantly reduced by pre-treatment with saliva from 7 subjects (enamel) or 6 subjects (dentine). Saliva from 1 subject resulted in significantly more enamel erosion than control. Conclusion: Saliva from different donors affords different levels of protection against erosion.

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