This study compared the effect of a copper phosphate cement (BCC) and a conventional glass ionomer cement (GIC) on carious dentine that remains under restorations in vivo. Using a split-mouth design, 45 primary molar pairs with dentine caries were sampled microbiologically. Without further removal of carious dentine, the molar pairs were randomly allocated to three restorative groups: (1) one cavity was lined with BCC and restored with GIC and the other was kept under review as an untreated control; (2) one cavity was restored with GIC, whilst the other was kept under review; (3) one cavity was lined with BCC and restored with GIC, whilst the other was filled with GIC. The dentine was re-sampled microbiologically at 1 month (30 pairs) and 6 months (15 pairs). BCC demonstrated a significant effect on the total anaerobic count over 1 month, when paired with both the control and GIC, whereas the antibacterial effects of GIC compared with no treatment were not statistically significant. In addition, BCC performed significantly better than no treatment in reducing mutans streptococci and lactobacilli over 1 month. Over 6 months, BCC caused a significantly greater reduction in mutans streptococci than GIC. In conclusion, BCC demonstrated a significant antibacterial effect on carious dentine in vivo.

This content is only available via PDF.
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.