The effect of calcium (Ca) concentrations and added ethanol on fluoride (F) depositions by experimental two–component rinses, each consisting of a Ca–containing and an F–containing component, was evaluated in an in vitro system. Among the tested rinses, a 3 mmol/l F two–component rinse with 200 mmol/l Ca and 10% v/v ethanol was found to produce the greatest F deposition relative to the F concentration in the rinse. Specifically, this rinse produced an F deposition that was about 7 times greater than a conventional 13.2–mmol/l sodium fluoride (NaF) rinse. In a second experiment, an in vitro pH cycling model was used to evaluate the potential anti–caries effects of 4 rinses: (1) placebo rinse (no F), (2) 13.2–mmol/l NaF rinse, (3) 52.6–mmol/l NaF rinse, and (4) the 3–mmol/l F two–component rinse in a 7–day in vitro pH cycling model. The changes in lesion mineral contents, delta(ΔZ), as assessed by quantitative microradiographic measurements, were as follows [mean ± standard deviation, n = 10]: (1) 72.5±10.2 µm, (2) 43.4±5.6 µm, (3) 17.3±10.2 µm and (4) 45.3±5.2 µm. These results showed that the 3–mmol/l F two–component rinse produced the same (p>0.05) protection against demineralization as did the 13.2–mmol/l NaF rinse which had 4 times the fluoride content. The results suggest that it is possible to formulate an effective low–F two–component rinse.

Keywords:
Fluoride rinse, Fluoride, Enamel, Mineralization, Calcium fluoride, Sodiumhexafluorosilicate, In vitro pH cyclic model
This content is only available via PDF.
2001
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.