The aim of this study was to evaluate the rates of salivary clearance at seven different locations in children. The diffusant was 1 mol/l KCl in a 1.0% agarose matrix, placed in small acrylic devices which could be fastened to the teeth with dental floss. The diffusion chambers were taken from the mouth at selected time intervals and the gels transferred quantitatively to flasks containing 400 ml of 100 ppm NaCl. The fluid was agitated intermittently for 1 h and analyzed for potassium by atomic absorption spectrophotometry. For 12 subjects (5 years of age), the clearance halftimes (the time for the initial potassium concentration to decrease by half) were lowest in the lower anterior lingual regions and were highest in the upper anterior buccal regions. When the salivary flow was stimulated, the clearance halftimes for the lower and upper anterior buccal sites in the 6 subjects without spaces between their anterior teeth were significantly higher than in the 6 subjects with spaces. The results show that the clearance halftime is longest for the upper anterior buccal site which is the site most prone to nursing bottle caries in the deciduous dentition.

This content is only available via PDF.
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.