5 breast-fed and 5 bottle-fed infants, all living in an area with 1 ppm F in the drinking water, were studied in a metabolic ward for 48 h. Samples were taken from breast milk in conjunction with suckling and the provided water-diluted baby formula. All urine and feces were collected. The F concentration in the breast milk ranged from 4 to 8 ng/ml (0.2–0.4 μM), resulting in a daily F dose of about 6 μg. The baby formula-fed infant received daily F doses ranging from 891 to 1,012 μg. Thus, the latter group received more than 150 times more F. The breast-fed infants were in a negative F balance, excreting more F than they ingested. The bottle-fed infants, on the other hand, retained more than 50% of the ingested F dose. The rapidly growing skeleton certainly enhances F retention, but a contributing factor might also be a slow elimination rate for F, caused by a not fully developed renal handling capacity for F at this early stage of life.

Keywords:
Baby formula, Breast milk, Fluoride, Fluoride excretion, Infants
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© 1984 S. Karger AG, Basel
1984
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