Studies were conducted to gain insights into how remineralization by fluorapatite (FAP) deposition onto hydroxyapatite (HAP) crystals might influence dissolution rate behavior and acid resistance. Dissolution rate behavior of compressed pellets was studied in 0.1 M acetate buffer, pH 4.5, ionic strength 0.5, using the rotating disk method. Attempts were made to determine the dissolution rate controlling phase by addition of common ions (Ca, P, F) to the buffer solution. Preliminary studies on HAP pellets and almost pure FAP pellets showed that FAP dissolved appreciable slower than HAP under the conditions used. The specific ion effects on FAP dissolution were consistent with predictions based on the expected ionic activity product of this mineral. The dissolution rate behavior of FAP-HAP mixtures in acid without common ions present in the buffer solution were interpreted as follows. With pellets prepared from HAP crystals onto which FAP had been precipitated, the first dissolving phase was FAP even at the lowest concentration of this phase. With pellets of mechanically mixed FAP and HAP the two components dissolved relatively independently. The reduced dissolution rates of FAP mineralized HAP compared with the mechanically mixed case and particularly with pellets of pure HAP may be of clinical significance. It is suggested that deposition of fairly low levels of FAP during in vivo remineralization may significantly decrease the tendency for caries formation.

Keywords:
Hydroxyapatite-fluorapatite mixtures, dissolution, Ion effects
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© 1983 S. Karger AG, Basel
1983
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