The aim of the present study was to examine the bioavailability of fluoride (F) from some infant food products containing considerable amounts of F. Three different solutions containing 5 mg F were administered on three separate occasions to 4 young volunteers. They consisted of 500 ml of a 10 ppm F water solution, 500 ml milk containing 10 ppm F and 500 ml of a baby formula prepared with a 10 ppm F solution. Plasma F and urinary F levels were subsequently monitored for 15 h. Pharmacokinetic analysis of the data was performed and F bioavailability calculated. The results show that 72% of all F in the milk- and 65% of all F in the water-diluted baby formula were absorbed. Results from in vitro recovery studies demonstrated a 100% F recovery from milk and a 90% F recovery from baby formula. An explanation for the contradictory findings in the in vivo experiments is discussed.

Keywords:
Baby foods, Bioavailability, Fluoride, Plasma, Urine
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© 1982 S. Karger AG, Basel
1982
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