In vitro topical application for 5 min or 6 h of 1.5 M ammonium fluoride with 1.5 M ammonium monofluorophosphate (MFP) to enamel was studied at pH 7.0 and 4.6. After 5-min treatments, fluoride penetrated over 10 μm, but less than 20 μm into the enamel. More fluoride deposition and penetration over 20 μm resulted from the 6-hour treatments. Most fluorapatite was formed after a 6-hour treatment with the neutral solution. Treated enamel surfaces were studied in the scanning electron microscope before and after KOH equilibration for removal of calcium fluoride. The electron micrographs were compared with others which were obtained from enamel treated for the same time with 1.5 M ammonium fluoride or 1.5 M ammonium MFP or 1.5 M ammonium fluoride with 1.5 M ammonium orthophosphate at pH 7.0 or 4.6. The findings indicated that the most extensive dissolution-precipitation reactions, with considerable calcium fluoride formation, occurred relative to the application of ammonium fluoride alone. Addition of ammonium MFP or orthophosphate to ammonium fluoride solutions reduced the extent of visible changes. Application of ammonium MFP alone caused very limited or no visible change.

Keywords:
Ammonium fluoride, Ammonium monofluorophosphate, Enamel, Fluoride, Monofluorophosphate, Topical application
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© 1982 S. Karger AG, Basel
1982
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