... myofibrillar protein content in the ‘compensatory’ LV hypertrophy of chronic AR. 7 08 1996 16 10 1996 21 11 2008 Protein synthesis Proteolysis Volume overload Valvular heart disease Cardiac hypertrophy Experimental model Rabbit CARDIOLOGY Roderick K. King Norman M. M agid George...

...) tracings: p = p₀e -t/τ + p 1 . Mean τ-values for LVP, ENDO and EPI during control were (mean ± 1 SD, ms): 38 ± 5, 60 ± 12, 83 ± 5; during volume overload: 55 ± 10, 72 ± 20, 85 ± 31 and after verapamil administration: 58 ± 13, 60 ± 17 and 73 ± 15, respectively. Relaxation time constants of ENDO and EPI were...

... in total cardiac protein and myosin heavy chain observed after 1 month of chronic volume overload was caused by a decrease in protein fractional degradation rates. The objective of the present study was to determine in vivo the relative contributions of protein synthesis and degradation of a variety...