... surgical patients with pure severe aortic regurgitation (PSAR). However, the efficacy of TAVR in younger patients with aortic regurgitation (AR) remains unclear. This study explored the therapeutic efficacy and safety of TAVR in these two groups and compared their outcomes. Methods: Patients with AR who...

... with the highest risk of mortality and rehospitalization. Safety and efficacy of early initiation of sacubitril/valsartan during the index hospitalization for acute decompensated heart failure (ADHF) is unclear. Therefore, we tested whether sacubitril/valsartan could result in a lower rate of a composite outcome...

... complications during pregnancy in women with congenital heart disease is low. In this largest analysis to date with a focus on parity in 307 women, the risk classification predicts the maternal outcome more than parity per se. If the first pregnancy is uneventful, the OR is 5.5 for an uneventful second...

... heart surgery and coronary artery bypass grafting. However, the impact of nonsignificant CAD on postoperative outcomes is not well understood. This study illustrated the epidemiological characteristics of CAD in China and investigated the impact of CAD on postoperative acute kidney injury (AKI...

...). In multivariate analysis, after adjustment for established outcome predictors including age, symptoms, EuroSCORE, and left ventricular size and function, LA enlargement >30 cm 2 was associated with increased mortality (adjusted HR = 2.20, 95% CI 1.03–4.90; p = 0.042), whereas LA enlargement between 26 and 30...

... ventricular systolic function. Currently, however, there is no recommendation for the best optimization method. This study aimed to compare the long-term clinical outcomes of 4 different CRT optimization methods. Methods: One hundred and twenty-four consecutive CRT patients with severe heart failure and left...

...Lifan Yang; Haiyan Chen; Wenzhi Pan; Lihua Guan; Xiaochun Zhang; Lei Zhang; Qinchun Jin; Daxin Zhou; Xianhong Shu; Junbo Ge Background: The aim of this study is to investigate the prevalence and outcome of tricuspid regurgitation (TR) in the Chinese population. Methods: The echocardiography...

... Analyzer (PRU: 85-208) and vasodilator-stimulated phosphoprotein P2Y 12 flow cytometry assay (platelet reactivity indices: 16-50%). Clinical outcomes will also be assessed, including major efficacy (composite of cardiac death, nonfatal myocardial infarction, repeat revascularization, or stroke) and safety...

... at admission was associated with substantially lower mortality: 9 versus 30%, p < 0.001 (table 3 ). Kaplan-Meier survival estimates through day 60 are shown in figure 1 b. Table 3 Treatment and outcome information by SBP and Sa O 2 groups Fig. 1 Outcome at 1 and 6 months...

... outcome. We focused on the interplay between the patient’s causal attribution of the infarction and compared this with the influence of background factors. The patient attribution most often predicted positive objective outcome and subjective functioning. This study shows that background factors...

...Holger Reinecke; Fritz Matzkies; Manfred Fobker; Günter Breithardt; Roland M. Schaefer Since recent studies demonstrated an impaired outcome after percutaneous coronary interventions (PCI) in patients with chronic renal failure but did not address the aetiology of renal failure, we now analysed...