...Jiling Ren; Lei Yang; Wencong Tian; Mengmeng Zhu; Jie Liu; Ping Lu; Jing Li; Liang Yang; Zhi Qi Objective: Exercise training (ET) provides a cardioprotective effect against pathological cardiac hypertrophy. Nitric oxide (NO) plays an important role in modulating cardiac hypertrophy. However, few...

...Dan Yang; Zhihong Liu; Zihe Yang Objectives: To investigate ghrelin levels in patients with idiopathic pulmonary arterial hypertension (IPAH) and the association of ghrelin with N-terminal brain natriuretic peptide (N-BNP), endothelin-1 (ET-1) and nitric oxide (NO). Methods: Plasma ghrelin, N-BNP...

...Arlene Bradley Levine; David Punihaole; T. Barry Levine Nitric oxide (NO) has long been known as endothelium-derived relaxing factor. It is a vasodilator, modulating vascular tone, blood pressure and hemodynamics, a role exploited by nitrate donor therapy for angina, heart failure, pulmonary...

..., instructions or products referred to in the content or advertisements. Coronary artery bypass grafting Nitric oxide Saphenous vein grafts Stenosis During surgery, 2 subjects from the control group died of ventricular fibrillation during measurement of nitrite concentration (25% of all the 8...

... of vascular smooth muscle and trafficking blood cells. Important endothelium-derived vasodilators are prostacyclin, bradykinin, nitric oxide and, independent of the former, endothelium-derived hyperpolarizing factor. In particular, nitric oxide inhibits cellular growth and migration. In concert...

...Alexander Tenenbaum; Enrique Z. Fisman; Michael Motro Since the recognition that L -arginine (LA) is the natural metabolic donor of nitric oxide, this amino acid has reached the medical spotlight. LA exerts favorable effects in the prevention and treatment of endothelial damage and the restoration...

...Ming-Guo Xu; Jie-Mei Wang; Long Chen; Yan Wang; Zhen Yang; Jun Tao Objectives: Berberine (BR) has a beneficial effect on endothelial function by increasing nitric oxide (NO), as NO plays a pivotal role in the regulation of endothelial progenitor cell (EPC) mobilization and function. The aim...

...Lior Sasson; Andrei Ureche; Gheorghe Manolache; Anatol Ciubotaru; Jeffrey S. Borer; Arie Schachner Objectives: Hypotension is common immediately following cardiopulmonary bypass. Experimentally, MTR-105 (S-ethylisothiuronium diethylphosphate), a fast-acting synthetic nitric oxide synthase inhibitor...

..., 90]. The ability of nitric oxide (NO) to promote smooth muscle relaxation in the coronary vasculature has made it ideal for the symptomatic relief of angina pectoris. However, new evidence indicates that NO has significant effects on the myocardium as well. Within the heart, NO production...

... to in the content or advertisements. Ageing Angiotensin converting enzyme inhibitors Arterial stiffness Atherosclerosis Clinical research, cardiovascular Elderly Endothelial function Nitric oxide Oxidative stress Ageing is one of the most important risk factors for cardiovascular disease...

... stress-mediated vascular protection is related to the upregulation of endothelial nitric oxide synthase expression in EPCs. The human EPCs exposed to in vitro shear stress levels of 5, 15 and 25 dyn/cm 2 for 4 h. In vitro shear stress, in a dose-dependent fashion, increased the endothelial nitric oxide...

...Costas Tentolouris; Dimitris Tousoulis; Graham Davies; Christodoulos Stefanadis; Athanasios Trikas; George Goumas; Pavlos Toutouzas We assessed the impact of systematic risk factors on the vasomotor effects of inhibition of nitric oxide synthesis. N G -monomethyl- L -arginine (LNMMA) was infused...

... subject groups. Reactive hyperemic FBF which represents maximum vasodilatory capacity did not differ among the three. To assess the role of nitric oxide in the augmented endothelium-dependent response in VAP, Ach-induced FBF response was determined before and after administration of the nitric oxide...