... profound effects on cardiomyocyte function and, as we are beginning to learn, on structure and growth. We now have strong evidence that converting enzyme inhibition at a tissue level may profoundly influence and modulate these actions of the cardiac renin-angiotensin system, particularly in the setting...

.... Angiotensin-II-forming enzyme Chymase Angiotensin-converting enzyme Mast cell Inflammatory cell Cardiac renin-angiotensin system Myocardial infarction Cardiac remodeling The cardiac renin-angiotensin system is activated following myocardial infarction (MI) in both humans [ 1 ]and experimental...