... levels and cardiac remodeling (left atrial [LA] enlargement and left ventricular hypertrophy [LVH]) in essential hypertension (EH) with normal renal function and explore the diagnostic values of FGF23 and B-type natriuretic peptide (BNP) in cardiac remodeling. Methods and Results: We enrolled 40 healthy...

... and experimental heart failure. Furthermore, LUM is important for survival and cardiac remodeling following pressure overload. We have recently reported that total lack of LUM increased mortality and left ventricular dilatation, and reduced collagen expression and cross-linking in LUM knockout mice after aortic...

...Lars Gullestad; Thor Ueland; Leif Erik Vinge; Alexandra Finsen; Arne Yndestad; Pål Aukrust Evidence from both experimental and clinical trials indicates that inflammatory mediators are of importance in the pathogenesis of chronic heart failure (HF) contributing to cardiac remodeling and peripheral...

.... Angiotensin-II-forming enzyme Chymase Angiotensin-converting enzyme Mast cell Inflammatory cell Cardiac renin-angiotensin system Myocardial infarction Cardiac remodeling The cardiac renin-angiotensin system is activated following myocardial infarction (MI) in both humans [ 1 ]and experimental...