.... 57.0%; p = 0.77). No association was found between traditional risk factors for coronary atherosclerosis and CMD regardless of whether CMD was structural or functional. In women, but not in men, older age and the presence of previous ischemic heart disease were associated with lower coronary flow...

... disorders, including atherosclerosis and dyslipidemia, myocardial injury, and heart failure. Key Messages: While substantial preclinical and clinical evidence suggests metformin as a potential cardiovascular protectant, large-scale randomized controlled trials are warranted to establish its clinical...

...Mehrian Jafarizade; Farima Kahe; Sadaf Sharfaei; Kaveh Momenzadeh; Anmol Pitliya; Farbod Zahedi Tajrishi; Preeti Singh; Gerald Chi Atherosclerosis is a chronic inflammation characterized by an imbalance between inhibitors and stimulators of the inflammatory system that leads to the formation...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Visual Abstract Visual Abstract. Atherosclerosis Coronary artery disease Coronary remodeling Fractional...

.... Computed tomographic coronary angiography Near-infrared spectroscopy-intravascular imaging Atherosclerosis Local haemodynamic forces There is growing evidence that vessel physiology and plaque characteristics are able to detect high-risk plaques that are likely to progress and cause...

...Andreas Synetos; Antonios Karanasos; Stauros Spyropoulos; Maria Gazouli; George Latsios; Konstantinos Toutouzas; Despina Perrea; Dimitrios Tousoulis; Ioannis A. Chloroyiannis Objectives: Atherosclerosis is almost absent in intramyocardial coronary arteries, while epicardial coronary arteries may...

... aortic valve disease (CAVD). The results of the experimental and clinical studies demonstrate that traditional risk factors initiate early atherosclerosis which over time differentiates to form bone in the heart causing clinical CAC and CAVD. Understanding the cellular mechanisms of cardiovascular...

...-to-mesenchymal transition (EndMT). Recently, TGF-β1-induced EndMT has been implicated in the pathogenesis of atherosclerosis (AS). It has been identified that apolipoprotein A1 (ApoA-I) obstructs TGF-β1-induced endothelial dysfunction, providing a protective effect for ECs and also anti-AS activity. However...

... (hTERT) gene would enhance EPC function in treating dietary-induced early atherosclerosis (AS). Methods: A dietary-induced early AS model was successfully constructed in 90 healthy male rats, while 30 healthy control (HC) rats were normally fed. Four experimental groups were constructed: an untreated HC...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Atherosclerosis Acute coronary syndrome Monocyte Urokinase-type plasminogen activator receptor The rupture...

..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Coronary artery disease Antiplatelet therapy Atherosclerosis Bleeding...

... from any ideas, methods, instructions or products referred to in the content or advertisements. THP-1 macrophages Oxidised low-density lipoprotein Brain natriuretic peptide Atherosclerosis Atherosclerosis is a progressive chronic inflammatory disease characterised by atherosclerotic...

...Nalini M. Rajamannan Atherosclerosis and osteoporosis are the leading causes of mortality and morbidity. The objective of this study was to test this hypothesis in experimental hypercholesterolemia to determine whether statins play a protective role in this process. LDLR -/- mice (n = 60) were...

...Ming Yuan; Hongjie Fu; Lifen Ren; Haichang Wang; Wenyi Guo Objective: High levels of soluble CD40 ligand (sCD40L) in the circulation have been suggested as an important indicator of cardiovascular diseases such as atherosclerosis and acute coronary syndromes. In the present study, we explored...

... to in the content or advertisements. Coronary artery disease Optical coherence tomography Atherosclerosis Plaque progression Atherosclerosis is a chronic inflammation resulting from arterial injuries caused by various risk factors. Its progression is indicated by plaque instability...

... analysis. Conclusion: In patients with BD, traditional risk factors associated with CAD were similar to what is expected in the overall population. However, the young age of patients with CAD in this population suggests an accelerated course of atherosclerosis in BD. [email protected] 20 05...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Ambulatory blood pressure monitoring Atherosclerosis Autonomic nervous system Blood pressure Cardiovascular risk...

... aneurysms actually protect against atherosclerosis. We have found that patients with ascending aneurysms have both decreased arterial calcification and carotid intima-media thickness, late and early indicators of atherosclerosis, respectively. In addition to these clinical data, we also found data regarding...

.... Stanford type A acute aortic dissection Atherosclerosis Metalloprotease-12 Macrophages It is well known that aneurysms/dissections occurring in the ascending thoracic aorta are associated with inherited connective tissue diseases [ 1 ]. However, most ascending dissections occur in the sixth...

... calcification to atherosclerosis and the interrelationship of VHD with other systems/organs are presented. Fig. 1 Factors contributing to the metamorphosis of the etiology of VHD (modified from [ 2 ]). Fig. 2 a Genetics of FMV/MVP. Arrow = proband, circle = females, squares = males, shaded...