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Keywords: Amlodipine
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Journal Articles
Journal Articles
Journal: Cardiology
Cardiology (1997) 88 (Suppl. 1): 17–23.
Published Online: 19 November 2008
... of angina. The results of two studies reviewed here, in which patients received concomitant treatment with a β-blocker, showed that the anti-anginal efficacy of nisoldipine CC, 40 mg once daily, measured at trough was comparable with amlodipine, 10 mg once daily, and with diltiazem retard, 120 mg twice...
Journal Articles
Journal Articles
Journal: Cardiology
Cardiology (1992) 80 (Suppl. 1): 31–36.
Published Online: 12 November 2008
...Darrell R. Abernethy Amlodipine is a low-clearance, dihydropyridine calcium antagonist. The slow rate of elimination (elimination half-life of 40-60 h) confers several pharmacokinetic characteristics that are not seen with other calcium-antagonist drugs. It has high oral bioavailability (60-80...
Journal Articles
Journal: Cardiology
Cardiology (1992) 80 (Suppl. 1): 54–59.
Published Online: 12 November 2008
...James Hosie; Douglas Bremner; Peter J. Fell; Ian G.V. James; Peter A. Saul; Stanley H. Taylor The frequency and severity of adverse effects during the first 14 days of treatment with amlodipine (5 mg once daily), nifedipine retard (20 mg twice daily) or placebo were compared in a multicentre, three...
Journal Articles
Journal Articles
Journal: Cardiology
Cardiology (1992) 80 (Suppl. 1): 26–30.
Published Online: 12 November 2008
...Stanley H. Taylor Once-daily administration of amlodipine is a highly effective treatment for patients with angina pectoris. This study has confirmed its benefit in a relatively large subgroup of patients with post-myocardial infarction angina. Amlodipine reduced the number of angina attacks...
Journal Articles
Journal: Cardiology
Cardiology (1992) 80 (Suppl. 1): 37–45.
Published Online: 12 November 2008
...Per Lund-Johansen; Per Omvik; William White; Øivind Digranes; Bjørn Helland; Odd Jordal; Tore Stray Haemodynamic responses at rest and during exercise were studied in 18 patients with essential hypertension following long-term treatment with amlodipine. Patients underwent a 2-week placebo run...
Journal Articles
Journal Articles
Journal Articles
Journal Articles
Journal: Cardiology
Cardiology (1998) 89 (Suppl. 1): 38–46.
Published Online: 03 March 1998
...-scale study demonstrated the safety of amlodipine, a long-acting dihydropyridine derivative, when used in patients with heart failure due to coronary artery disease. Furthermore, this study demonstrated a substantial reduction in mortality in patients with CHF due to nonischemic cardiomyopathy...
Journal Articles
Journal: Cardiology
Cardiology (1998) 89 (Suppl. 1): 23–32.
Published Online: 03 March 1998
... test variables regardless of demographic subpopulation or background therapy. Significant reductions in weekly anginal attacks, silent ischemic parameters, heart rate (HR) and rate-pressure product were also observed. Two active-controlled trials compared mibefradil 100 mg with amlodipine 10 mg...
Journal Articles
Journal: Cardiology
Cardiology (1998) 89 (2): 111–118.
Published Online: 13 February 1998
...Alexander N. Orekhov; Vladimir V. Tertov; Elena M. Pivovarova Four antihypertensive agents – amlodipine, verapamil, propranolol and perindoprilat – were studied in human cell cultures. Antiatherogenic activity was investigated using uninvolved human aortic smooth muscle intima cells and atherogenic...