Objectives: ST-segment elevation myocardial infarction (STEMI) can be associated with many conduction disturbances including complete atrioventricular block (CAVB). CAVB complicating STEMI resulted in an increased mortality before the modern era of primary percutaneous coronary intervention (PCI). The aim of this study was to ascertain the rate and risk factors for CAVB in STEMI patients undergoing rapid reperfusion with PCI. Methods: We analyzed 223 patients presenting with STEMI. Patient characteristics, procedural characteristics, and in-hospital data were compared between patients with and without CAVB. Results: Out of 223 patients, 174 underwent PCI; the majority (87%) was African-American. CAVB was present in 8 patients (4.6%), and 6 of them had RCA occlusion. Independent predictors of CAVB included diabetes mellitus, female gender, lower systolic and diastolic blood pressure, and inferior-lateral/lateral STEMI. Ten patients (5.7%) required temporary pacing at presentation; only 1 patient required permanent pacing before discharge. No patient with anterior STEMI developed CAVB. Conclusions: The incidence and in-hospital mortality rate of CAVB in patients with STEMI who underwent primary PCI was reduced when compared to data from the thrombolytic era. This may be due to faster flow recovery in the infarct-related artery achieved with PCI.

1.
Abidov A, Kaluski E, Hod H, et al: Influence of conduction disturbances on clinical outcome in patients with acute myocardial infarction receiving thrombolysis (results from the ARGAMI-2 study). Am J Cardiol 2004; 93: 76–80.
2.
Aplin M, Engstrøm T, Vejlstrup NG, Clemmensen P, Torp-Pedersen C, Køber L: Prognostic importance of complete atrioventricular block complicating acute myocardial infarction. Am J Cardiol 2003; 92: 853–856.
3.
Berger P, Ryan T: Incidence and prognostic implications of heart block complicating inferior myocardial infarction treated with thrombolytic therapy: results from TIMI II. J Am Coll Cardiol 1992; 30: 533–540.
4.
Clemmensen P, Clemmensen P, Bates ER, et al: Complete atrioventricular block complicating inferior wall acute myocardial infarction treated with reperfusion therapy. Am J Cardiol 1991; 67: 225–230.
5.
Gang UJ, Hvelplund A, Pedersen S, et al: High-degree atrioventricular block complicating ST-segment elevation myocardial infarction in the era of primary percutaneous coronary intervention. Europace 2012; 14: 1639–1645.
6.
Goldberg RJ, Zevallos J, Yarzebski J, et al: Prognosis of acute myocardial infarction complicated by complete heart block (the Worcester Heart Attack Study). Am J Cardiol 1992; 69: 1135–1141.
7.
Harpaz D, Behar S, Gottlieb S, Boyko V, Kishon Y, Eldar M: Complete atrioventricular block complicating acute myocardial infarction in the thrombolytic era. J Am Coll Cardiol 1999; 34: 1721–1728.
8.
Kim KH, Jeong MH, Ahn Y, et al: Differential clinical implications of high-degree atrioventricular block complicating ST-segment elevation myocardial infarction according to the location of infarction in the era of primary percutaneous coronary intervention. Korean Circ J 2016; 46: 315–323.
9.
Meine TJ, Al-Khatib SM, Alexander JH, Granger CB, White HD, Kilaru R, Williams K, Ohman EM, Topol E, Califf RM: Incidence, predictors, and outcomes of high-degree atrioventricular block complicating acute myocardial infarction treated with thrombolytic therapy. Am Heart J 2005; 149: 670–674.
10.
Nguyen HL, Lessard D, Spencer FA, Yarzebski J, Zevallos JC, Gore JM, Goldberg RJ: Thirty-year trends (1975–2005) in the magnitude and hospital death rates associated with complete heart block in patients with acute myocardial infarction: a population-based perspective. Am Heart J 2008; 156: 22.
11.
Shacham Y, Leshem-Rubinow E, Steinvil A, Keren G, Roth A, Arbel Y: High degree atrioventricular block complicating acute myocardial infarction treated with primary percutaneous coronary intervention: incidence, predictors and outcomes. Isr Med Assoc J 2015; 17: 298–301.
12.
Rathore SS, Gersh BJ, Berger PB, et al: Acute myocardial infarction complicated by heart block in the elderly: prevalence and outcomes. Am Heart J 2001; 141: 47–54.
13.
Birnbaum Y, Sclarovsky S, Herz I, Zlotikamien B, Chetrit A, Olmer L, Barbash GI: Admission clinical and electrocardiographic characteristics predicting in-hospital development of high-degree atrioventricular block in inferior wall acute myocardial infarction. Am J Cardiol 1997; 80: 1134–1138.
14.
Hreybe H, Saba S: Location of acute myocardial infarction and associated arrhythmias andoutcome. Clin Cardiol 2009; 32: 274–277.
15.
Harikrishnan P, Gupta T, Palaniswamy C, et al: Complete heart block complicating ST-segment elevation myocardial infarction: temporal trends and association with in-hospital outcomes JACC Clin Electrophysiol 2015; 1: 529–538.
16.
O’Gara PT, Kushner FG, Ascheim DD, et al: 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation 2013; 127: 529–555.
17.
Waller BF, Orr CM, Slack JD, Pinkerton CA, Van Tassel J, Peters T: Anatomy, histology, and pathology of coronary arteries: a review relevant to new interventional and imaging techniques. Part I. Clin Cardiol 1992; 15: 451–457.
18.
Simons GR, Sgarbossa E, Wagner G, Califf RM, Topol EJ, Natale A: Atrioventricular and intraventricular conduction disorders in acute myocardial infarction: a reappraisal in the thrombolytic era. Pacing Clin Electrophysiol 1998; 21: 2651–2663.
19.
Gómez-Talavera S, Vivas D, Perez-Vizcayno MJ, Hernández-Antolín R, Fernández-Ortíz A, Bañuelos C, Escaned J, Jiménez-Quevedo P, Viliani D, Vilacosta I, Macaya C, Alfonso F: Prognostic implications of atrio-ventricular block in patients undergoing primary coronary angioplasty in the stent era. Acute Card Care 2014; 16: 1–8.
20.
Ho KW, Koh TH, Wong P, et al: Complete atrioventricular block complicating acute anterior myocardial infarction can be reversed with acute coronary angioplasty. Ann Acad Med Singapore 2010; 39: 254–257.
21.
Zhong L, Gao Y, Xia H, Li X, Wei S: Percutaneous coronary intervention delays pacemaker implantation in coronary artery disease patients with established bradyarrhythmias. Exp Clin Cardiol 2013; 18: 17–21.
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.