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Keywords: p38 MAPK
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Cellular Physiology and Biochemistry (2017) 43 (4): 1369–1380.
Published Online: 09 October 2017
.... In addition, p38 MAPK was elevated in NS1-expressing Neuro2a cells. Reduced iNOS expression and subdued cellular senescence effect was found in p38 MAPK inhibitor-treated NS1-expressing Neuro2a cells. Conclusion: Our results suggest that H7N9/NS1 protein increases the iNOS expression and NO release in Neuro2a...
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Cellular Physiology and Biochemistry (2017) 41 (1): 91–100.
Published Online: 17 January 2017
... the expression and secretion of IL-6 through activating extracellular signal-related kinase (ERK), p38 mitogen-activated protein kinase (p38 MAPK) and nuclear factor-kappa B (NF-κB). These activations can be blocked by specific inhibitors of the three pathways. Conclusions: HBcAg actives p38, ERK1/2 and NF-κB...
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Cellular Physiology and Biochemistry (2015) 37 (1): 94–104.
Published Online: 17 August 2015
.... Neuropeptide Y Cardiac hypertrophy Calcineurin p38 MAPK Neuropeptide Y (NPY), a 36-amino-acid sympathetic neurotransmitter, is known to be widely distributed in the mammalian central and peripheral nervous system [ 1,2 ] and is an important modulator in a variety of physiological actions, including...
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Cellular Physiology and Biochemistry (2015) 36 (3): 937–946.
Published Online: 12 June 2015
..., and examined the activation of p38 MAPK, p42/p44 MAPK and SMAD3. We used a specific inhibitor PD98059 to antagonize phosphorylation of p42/p44 MAPK, or used a specific inhibitor SN203580 to antagonize phosphorylation of p38 MAPK, or used a specific inhibitor SIS3 to antagonize phosphorylation of SMAD3. We...
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Cellular Physiology and Biochemistry (2014) 34 (5): 1711–1722.
Published Online: 12 November 2014
..., but the underlying mechanism remained unclear. Methods: Immunoprecipitation and immunofluorescence were performed to examine the interaction of WWOX and P38 MAPK. Western blot was carried out to detect the expression of ATF2 and eIF-4E. MTT, colony formation, and Annexin V-FITC assays were performed to detect...
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Cellular Physiology and Biochemistry (2012) 30 (5): 1181–1190.
Published Online: 12 October 2012
...-regulation of cellular apoptosis and an apparent increase in the expression of the p38 mitogen-activated protein kinase (p38 MAPK). Further, the changes in C33a and SiHa cells viability, migration and proliferation observed upon overexpression of gC1qR could be abrogated using the p38 MAPK inhibitor SB202190...
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Cellular Physiology and Biochemistry (2012) 30 (2): 334–346.
Published Online: 25 June 2012
... that U0126, an inhibitor of ERK1/2 upstream kinase MEK1/2, blocked both H 2 O 2 -induced inhibition of SP-A and SP-B gene expression, whereas SB203580, an inhibitor of p38 MAPK, partially blocked H 2 O 2 -mediated inhibition of SP-A gene expression but not SP-B expression. In contrast, AG-490, a specific...
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Cellular Physiology and Biochemistry (2011) 27 (5): 463–470.
Published Online: 15 June 2011
... (p38 MAPK). However, the molecular mechanisms that regulate the stability of atrogin-1 protein remain unclear. Methods: 293T and cardiac H9c2 cells were transfected with plasmids as indicated. The in vivo and in vitro ubiquitination assay and pulse-chase analysis were performed to detect...
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