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Keywords: p21
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Cellular Physiology and Biochemistry (2018) 49 (2): 463–478.
Published Online: 29 August 2018
... polycomb repressive complex 2 subunit), and chromatin immunoprecipitation (ChIP) assay was conducted to examine whether SNHG6 could repress p21 transcription by recruiting EZH2 to the p21 promoter. Results: Here we found that SNHG6 was upregulated and its expression levels were positively correlated...
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Cellular Physiology and Biochemistry (2018) 46 (4): 1606–1616.
Published Online: 20 April 2018
... was used to determine the expression level of p21 in bladder cancer cells. Results: Cdr1as was significantly down-regulated in bladder cancer tissues compared with adjacent normal tissues. Overexpression of Cdr1as inhibited the proliferation, invasion and migration of bladder cancer cells in vitro...
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Cellular Physiology and Biochemistry (2016) 38 (3): 1003–1014.
Published Online: 04 March 2016
...-dihydrotestosterone (DHT) or nonsteroidal antagonist bicalutamide or untreated. The effects of AR on cell viability and apoptosis were determined by MTT assay, cell counting, flow cytometry analysis and protein expression of p53, p73, p21 and Cyclin D1 were analyzed by western blotting. The bindings of AR to p73...
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Cellular Physiology and Biochemistry (2015) 37 (1): 35–42.
Published Online: 12 August 2015
...-cycle suppressor p21 and p27, and increasing apoptosis-associated protein Bcl-2. MiR203 may also inhibit cell metastasis through suppressing matrix metalloproteinase 2 (MMP2), MMP7 and MMP9. Conclusion: Our data thus highlight miR203 as a novel therapeutic target for breast cancer. 17 03 2015...
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Cellular Physiology and Biochemistry (2015) 36 (2): 763–772.
Published Online: 22 May 2015
... metabolism to promote lactate production. This effect is caused by mitochondrial damage, not an alteration to lactate dehydrogenase activity. As a result of the mitochondrial damage, cell proliferation was inhibited and was associated with an elevation in p21/p27 proteins, which are both important cell cycle...
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Cellular Physiology and Biochemistry (2015) 35 (5): 1756–1763.
Published Online: 23 March 2015
..., instructions or products referred to in the content or advertisements. Glioblastoma multiforme (GBM) Transforming growth factor β (TGFβ) SMAD2 SMAD3 p21 Cancer cell growth Glioblastoma multiforme (GBM), which is named as glioblastoma by WHO, is the most common and most malignant primary...
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Cellular Physiology and Biochemistry (1999) 9 (3): 117–125.
Published Online: 08 September 1999
.... Although proteasome inhibitors induced p53 accumulation in a cell line retaining wild-type p53 activity, p53 activity was dispensable for apoptosis since transdominant-negative p53 abrogated p53-dependent p21 induction but did not modulate apoptosis. Further, p21 was induced by higher concentrations...