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Keywords: cAMP
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Cellular Physiology and Biochemistry (2018) 45 (6): 2516–2528.
Published Online: 27 March 2018
... by stimulation of adenylyl cyclase, causing an increase of the intracellular cAMP concentration, activation of the intracellular cAMP effectors protein kinase A (PKA) and Epac, and an efflux of cAMP, the function of which is still unclear. Methods: Activation of adenylyl cyclase by GsPCR agonists or cholera...
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Cellular Physiology and Biochemistry (2015) 36 (3): 866–883.
Published Online: 27 May 2015
... activation of the CD95 death receptor at the level of association between CD95 and the epidermal growth factor receptor. This was due to a rapid TUDC-induced β 1 -integrin-dependent cyclic AMP (cAMP) signal with induction of the dual specificity mitogen-activated protein (MAP) kinase phosphatase 1 (MKP-1...
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Cellular Physiology and Biochemistry (2012) 30 (5): 1227–1240.
Published Online: 15 October 2012
... and mammalian cells. D553N channels generate currents with reduced amplitude, while the kinetics of activation and deactivation are not altered. While the regulation of D553N by tyrosine kinases is normal, we observed a change in the cAMP regulation which however cannot account for the strong loss-of-function...
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Cellular Physiology and Biochemistry (2012) 29 (3-4): 511–522.
Published Online: 03 April 2012
... amplitude (CBA) of isolated mouse bronchiolar ciliary cells were measured using a light microscope equipped with a high-speed camera (500 Hz). Procaterol (aβ 2 -agonist) increased CBA and CBF in a dose dependent manner via cAMP. The time course of CBA increase is distinct from that of CBF increase...
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Cellular Physiology and Biochemistry (2009) 24 (1-2): 53–64.
Published Online: 01 July 2009
... suppressed ammonia-induced blebbing in the microglia cell line, BV-2. In further experiments, we elucidated the common mechanism of Cl channel activity and cyclic adenosine 3’,5’-monophosphate (cAMP)-dependent pathway on cell blebbing. These experiments indicated that perfusion of cells with cAMP...
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Cellular Physiology and Biochemistry (2008) 22 (5-6): 487–496.
Published Online: 09 December 2008
... type, express the cystic fibrosis transmembrane regulator and the epithelial Na + channel, and display NPPB and amiloride-sensitive transepithelial transport when stimulated with [Arg 8 ]-vasopressin. [Arg 8 ]-vasopressin binding to its receptor on the basolateral membrane of MDCK-C7 results in cAMP...
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Cellular Physiology and Biochemistry (1993) 3 (1): 89–96.
Published Online: 04 September 2008
... of cell membrane potential are elicited by acute addition of 0.5% fetal calf serum. Acute addition of cAMP (1 mmol/l), on the other hand, did not elicit oscillations of cell membrane potential. The involvement of calmodulin was excluded by the use of trifluoperazine (10 µmol/l), pimozide (1 µmol/l...
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Cellular Physiology and Biochemistry (1995) 5 (6): 380–384.
Published Online: 04 September 2008
...Alexander V. Sirotkin The aim of our in vitro experiments was to determine the involvement of cyclic nucleotides in mediating the effects of oxytocin (OT) and arginine vasopressin (AVP) on bovine ovarian cells. The influence of OT and AVP (1–100,000 ng/ ml) on cGMP and cAMP production by bovine...
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Cellular Physiology and Biochemistry (1997) 7 (1): 53–60.
Published Online: 04 September 2008
.... The effect is reversible under the in vitro conditions used, indicating that it is not due to the glycation of proteins that can occur with elevated glucose levels. Exposure of NK cells to 44 m M glucose results in a significant elevation of cAMP, indicating that elevation of this potent inhibitor of NK...
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Cellular Physiology and Biochemistry (1998) 8 (6): 314–327.
Published Online: 12 February 1999
... influx, or the phorbol esther 12-O-tetradecanoylphorbol-13-acetate (PMA), a protein kinase C (PKC) activator, increased the activity of the antiporter. Both effects were abrogated by inhibition of the Na + /K + -ATPase with ouabain. The increase in cAMP levels did not affect the effect of PMA on pHi...
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Cellular Physiology and Biochemistry (1998) 8 (4): 212–223.
Published Online: 03 July 1998
... in amphibian skin. The effect of AP on G Cl was slowly and incompletely reversible even after brief exposure to the agent. Serosal application of AP had similar, albeit delayed effects on both Na + and Cl – transport. AP did not interfere with the Cl – pathway after it was opened by 100–300 µ M CPT-cAMP...