... to in the content or advertisements. Epidermal stem cells miR-203 Hes1 Wound healing Scar One of the most common complications during wound healing is the formation of scars. The adverse physiological and psychological effects that are associated with scars formation following the healing...

... skin wound healing. One of the mechanisms underlying the beneficial effects of acute hypoxia on wound healing may be increased hypoxia-inducible factor-1 (HIF-1α) expression. HIF-1α may affect the wound-healing process through many aspects, including angiogenesis, metabolism, and extra-cellular matrix...

... analysis, wound healing migration assays, immunoprecipitation, and chromatin immunoprecipitation assay were performed to investigate the effect of high glucose on hUCB-MSC migration. Additionally, hUCB-MSC transplantation was performed in the mouse excisional wound splinting model. Results: High...

...Yang Bai; Rui Xu; Xueyuan Zhang; Xiaorong Zhang; Xiaohong Hu; Yashu Li; Haisheng Li; Meixi Liu; Zhenggen Huang; Rongshuai Yan; Weifeng He; Gaoxing Luo; Jun Wu Backgroud/Aims: The effects of rapamycin (RPM) on wound healing have been previously studied. However, reciprocal contradictory data have...

... or advanced therapies have been suggested, but with little overall efficacy. Since the 1980s extracorporal shock wave therapy (ESWT) has gained interest as treatment for specific indications. Here, we report that patients with CLU showed wound healing after ESWT and investigated the underlying molecular...

...Tingyu Ke; Mei Yang; Duo Mao; Meifeng Zhu; Yongzhe Che; Deling Kong; Chen Li Background/Aims: Impaired diabetes wound healing can often lead to serious complications and remains a major health concern due to the lack of effective therapeutic approaches. Compromised angiogenesis, disrupted growth...

...Wael N. Hozzein; Gamal Badr; Ahmad A. Al Ghamdi; Ayat Sayed; Noori S. Al-Waili; Olivier Garraud Background/Aims : Impaired wound healing is considered to be one of the most serious complications associated with diabetes as it significantly increases the susceptibility of patients to infection...

... therapeutic modalities targeting at enhancing wound healing, the development of novel approaches for this pathology remains a clinical challenge. The time-consuming conservative wound management is mainly restricted to wound repair rather than restitution of the tissue integrity (the so-called “restitutio ad...

... ]. Wound healing is a complex process that involves signaling cascades, control of apoptosis, cell migration, differentiation, and re-creation of tissue integrity. Reactive oxygen species (ROS) are produced intracellularly, in association with lipid peroxides, oxidases, and such redox-sensitive proteins...

... were embedded on the microscope slides using fluorescent mounting medium (DAKO Deutschland GmbH, Hamburg, Germany). Cell migration Wound healing Mucosal injury Restitution TFF1 Trefoil factor Gastrokine 2 Survivin LGR5 EMT siRNA © 2013 S. Karger AG, Basel 2013 Open Access...

...Leandra Sepe; Maria Carla Ferrari; Concita Cantarella; Francesca Fioretti; Giovanni Paolella Background : Cell migration is essential in physiological and pathological processes, such as wound healing and metastasis formation. Ras involvement in these processes has been extensively demonstrated...

...Jun Li; Ping Li; Yan Zhang; Gong-Bo Li; Feng-tian He; Yuan-Guo Zhou; Kang Yang; Shuang-Shuang Dai Background/Aim : Both peroxisome proliferator-activated receptor (PPAR) δ and Ski are investigate the interaction of PPARδ and Ski and this interaction-associated effect in wound healing. Methods...

.... Whey proteins (WPs) enhance immunity during early development and have a protective role in some immune disorders. The effect of camel WPs on wound healing in a streptozotocin-induced type 1 diabetic mice model was investigated. Sixty male mice were equally distributed into 3 experimental groups: group...

..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Cell migration Wound healing Restitution EGF CXCR4 EMT Metastasis Tight...

... including wound healing. We previously showed that PDGFRα signaling is coordinated by the primary cilium in quiescent cells. However, little is known about the function of the primary cilium in cell migration. Here we used micropipette analysis to show that a normal chemosensory response to PDGF-AA...

...Eva B. Znalesniak; Uwe Dürer; Werner Hoffmann Rapid repair by cell migration, a process called “restitution”, is essential for wound healing of mucous epithelia. Here, an established in vitro model for restitution, i.e., migration of the non-transformed intestinal epithelial cell line IEC-18 after...