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Journal Articles

Ursodeoxycholic Acid Attenuates Acute Aortic Dissection Formation in Angiotensin II-Infused Apolipoprotein E-Deficient Mice Associated with Reduced ROS and Increased Nrf2 Levels

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Wanjun Liu, Bei Wang, Tao Wang, Xintian Liu, Xingwei He, Yujian Liu, Zhuxi Li, Hesong Zeng
Journal: Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2016) 38 (4): 1391–1405.
https://doi.org/10.1159/000443082
Published Online: 30 March 2016
..., oxidative stress is activated and regulates apoptosis and inflammation. Excessive apoptosis promotes aortic inflammation and degeneration, leading to AAD formation. This study aimed to clarify role of oxidative stress in the pathogenesis of AAD and whether the antioxidant ursodeoxycholic acid (UDCA...
View articletitled, Ursodeoxycholic Acid Attenuates Acute Aortic Dissection Formation in Angiotensin II-Infused Apolipoprotein E-Deficient Mice Associated with Reduced ROS and Increased Nrf2 Levels
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