... cells (PBMCs) from active tuberculosis (TB) patients to identify novel biomarkers for TB. Methods: Expression profile of circRNAs in PBMCs from 3 active pulmonary TB patients and 3 healthy controls were analyzed by microarray assay. Six circRNAs were selected for validation using real time-quantitative...

...Yunan Zhu; Hongyu Jia; Jianing Chen; Guangying Cui; Hainv Gao; Yingfeng Wei; Chong Lu; Lin Wang; Toshimitsu Uede; Hongyan Diao Background/Aims: Osteopontin (OPN) expression is increased during the course of various chronic inflammatory diseases, including tuberculosis (TB). However, its prognostic...

...Rômulo J. Soares-Bezerra; Rosa T. Pinho; Rodrigo da C. Bisaggio; Thereza Christina Benévolo-de-Andrade; Luiz A. Alves Treatment for tuberculosis is effective with the use of proper antibiotics, but the number of drug-resistant cases is increasing. Drug resistance occurred in 650,000 cases of the 20...

...Tieshan Teng; Jiafa Liu; Hongping Wei Mycobacterium tuberculosis is the major pathogen of tuberculosis (TB). With the growing problem of M. tuberculosis resistant to conventional antibiotics, especially multi-drug resistant tuberculosis (MDR-TB) and extensively-drug resistant tuberculosis (XDR-TB...

..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Mycobacterium tuberculosis NOD2 Sentinel Innate immune Tuberculosis...