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Keywords: TGF-β1
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Cellular Physiology and Biochemistry (2018) 49 (3): 848–868.
Published Online: 05 September 2018
... matrix (ECM). Current literature sheds new light on the critical role of ECM signaling coupled with mechanotransduction in driving myofibroblastic activation. In particular, transforming growth factor β1 (TGF-β1) and extra domain A containing fibronectin (EDA-FN) are thought to be the primary ECM...
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Cellular Physiology and Biochemistry (2018) 45 (1): 250–257.
Published Online: 22 January 2018
... the effects of hypoxia on myofibroblast transformation of TGF-β1-induced cardiomyocyte H9c2 cells. Methods: H9c2 cells were cultured for intermittent hypoxia treatment and TGF-β1 treatment. α-Smooth muscle actin (α-SMA) expression was examined by western blotting and immunofluorescence after treatment...
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Cellular Physiology and Biochemistry (2017) 42 (6): 2207–2219.
Published Online: 16 August 2017
... was permanently ligated of mice. First, we explored the expression of miR-21 in the infarcted zone in mice model of MI via RT-qPCR. Next, we examined the effects of TGF-β1 on miR-21 expression in cardiac fibroblasts (CFs). Then, CFs were infected with miR-21 mimics or miR-21 inhibitors to investigate the effects...
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Cellular Physiology and Biochemistry (2017) 42 (4): 1469–1480.
Published Online: 18 July 2017
...Xu Lin; Xintng Zhen; Haiting Huang; Haohao Wu; Yanwu You; Pengwei Guo; Xiangjun Gu; Fafen Yang Background/Aims: Transforming growth factor beta 1 (TGF-β1) plays a critical role in the pathogenesis of glomerulosclerosis. The purpose of this study was to examine the effects of inhibition of miR-155...
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Cellular Physiology and Biochemistry (2017) 41 (3): 1147–1155.
Published Online: 28 February 2017
..., FSL further influenced key molecular mediators during development of FSGS. i.e., it specifically restored the impaired nephrin and attenuated the exaggerated transforming growth factor beta 1 (TGF-β1), caspase-9 and desmin thereby improving worsened renal functions and glomerular injury. Consistent...
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Cellular Physiology and Biochemistry (2017) 41 (1): 163–172.
Published Online: 18 January 2017
...Haiting Huang; Yanwu You; Xu Lin; Chunrong Tang; Xiangjun Gu; Meiying Huang; Youling Qin; Junhua Tan; Feifan Huang Background/Aims: Transforming growth factor beta 1 (TGF-β1) plays a critical role in the pathogenesis of glomerulosclerosis. The purpose of this study was to examine the effects...
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Cellular Physiology and Biochemistry (2016) 39 (1): 33–46.
Published Online: 20 June 2016
...), and transforming growth factor beta-1 (TGF-β1) were determined by an enzyme-linked immunosorbent assay (ELISA). Western blotting was performed to determine the protein expression of TGF-β1, fibrinogen, and α-smooth muscle actin (α-SMA) in rat peritoneal adhesion tissue. Real-time RT-PCR was performed to quantify...
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